Maynard C, Fisher L D, Passamani E R, Pullum T
Circulation. 1986 Jul;74(1):64-71. doi: 10.1161/01.cir.74.1.64.
In this paper we examine the relationship between risk factors and angiographically determined coronary artery disease for blacks and whites enrolled in the Coronary Artery Surgery Study (CASS). Analysis of data from the CASS registry indicated that blacks had a higher incidence of hypertension and current cigarette smoking than did whites in CASS and that chest pain was the major reason that both blacks and whites underwent coronary angiography for suspected or proven coronary disease. The CASS data also showed that, despite high levels of risk factors and chest pain, blacks had minimal or absent coronary disease. The results of this study raise several questions. First, to what extent are blacks in CASS representative of blacks in the general population and blacks undergoing coronary angiography? Additionally, are risk factors for coronary artery disease different for blacks than for whites? And finally, how does the physician effectively treat the black patient with high levels of risk factors and minimal coronary disease?
在本文中，我们研究了参与冠状动脉手术研究（CASS）的黑人和白人中危险因素与血管造影确定的冠状动脉疾病之间的关系。对CASS登记数据的分析表明，在CASS中，黑人的高血压和当前吸烟发生率高于白人，并且胸痛是黑人和白人因疑似或确诊冠心病而接受冠状动脉造影的主要原因。CASS数据还显示，尽管存在高水平的危险因素和胸痛，但黑人的冠心病程度较轻或没有冠心病。这项研究的结果提出了几个问题。首先，CASS中的黑人在多大程度上代表了一般人群中的黑人以及接受冠状动脉造影的黑人？此外，黑人的冠状动脉疾病危险因素与白人不同吗？最后，医生如何有效地治疗具有高水平危险因素且冠心病程度较轻的黑人患者？
