Onwuanyi Anekwe E, Clarke Aubrey, Vanderbush Eric
Morehouse School of Medicine, Division of Cardiology, Piedmont Hall, 720 Westview Drive SW, Atlanta, GA 30310, USA.
J Natl Med Assoc. 2003 Dec;95(12):1146-51.
Although mortality from cardiovascular diseases (CVDs) has been declining, it remains the leading cause of death among urban U.S. blacks. McCord and Freeman reported CVD as the major contributor to excess mortality in Central Harlem. However the disease-specific CVD mortality was not assessed. Thus, it was unclear what the distribution of specific CVDs was in Central Harlem and their contribution to excess mortality. We reviewed the vital statistics records of New York City (NYC) Department of Health for 1990 and identified all cases in which the cause of death was coded as cardiovascular (International Classification of Diseases-ICD, 9th Revision, codes 391, 393-398, 401-404, 410, 411, 414-417, 420-438 and 440-444). The total and disease-specific CVD mortality for NYC and Central Harlem were calculated using the appropriate 1990 census data as the denominator. Central Harlem residents aged between 25-64 years were at least twice as likely to die from cardiovascular causes, compared to NYC residents. Hypertension-related deaths, ICD codes 401 (essential hypertension), 402 (hypertensive heart disease), 403 (hypertensive renal disease), and 404 (hypertensive heart and renal disease), were the major cause of excess death for men and women in Central Harlem. These findings show the importance of hypertension as the main determinant of the excess cardiovascular mortality in urban blacks and suggest an increased risk of cardiovascular death in blacks residing in Central Harlem.
尽管心血管疾病(CVDs)导致的死亡率一直在下降,但它仍是美国城市黑人中的主要死因。麦科德和弗里曼报告称,心血管疾病是哈莱姆中心区超额死亡率的主要原因。然而,并未对特定疾病的心血管疾病死亡率进行评估。因此,尚不清楚哈莱姆中心区特定心血管疾病的分布情况及其对超额死亡率的影响。我们查阅了纽约市(NYC)卫生部1990年的人口动态统计记录,确定了所有死亡原因被编码为心血管疾病的病例(国际疾病分类-第9版,代码391、393 - 398、401 - 404、410、411、414 - 417、420 - 438以及440 - 444)。使用1990年适当的人口普查数据作为分母,计算了纽约市和哈莱姆中心区总的以及特定疾病的心血管疾病死亡率。与纽约市居民相比,年龄在25 - 64岁之间的哈莱姆中心区居民死于心血管疾病的可能性至少高出两倍。与高血压相关的死亡,国际疾病分类代码401(原发性高血压)、402(高血压性心脏病)、403(高血压性肾病)以及404(高血压性心肾病),是哈莱姆中心区男性和女性超额死亡的主要原因。这些发现表明高血压作为城市黑人超额心血管死亡率的主要决定因素的重要性,并提示居住在哈莱姆中心区的黑人心血管死亡风险增加。