School of Public Health, Kunming Medical University, Kunming, Yunnan, China.
NHC Key Laboratory of Drug Addiction Medicine, Kunming Medical University, Kunming, Yunnan, China.
Front Public Health. 2023 Apr 5;11:1043222. doi: 10.3389/fpubh.2023.1043222. eCollection 2023.
Adverse childhood experiences (ACEs) are associated with an increased risk of poly-substance use among drug-using adults. However, there is a paucity of literature on a direct or indirect relationship between ACEs and drug use patterns. We thus aimed to identify the pathway of effects of ACEs on drug use patterns in adults by the structural equation model (SEM).
A cross-sectional study was conducted by respondent-driving sampling and consecutive sampling among adult drug users in Southwest China in 2021. Descriptive, univariate, and SEM analyses were performed by R software 4.2.1.
Of 406 participants recruited from a drug abuse clinic, the average age was 34 years. The majority of the participants were male patients (98.3%) from ethnic minorities (79.6%), who were unmarried (71.6%) and employed (81.2%). Nearly 95.5% experienced ACEs with 46.6% of them reporting four or more ACEs. The median value of self-perception of drug abuse score, friend drug use score, and drug use score was 8.0 (3.0, 11.0), 1.0 (0.0, 1.0), and 1.0 (1.0, 2.0) respectively. In the confirmatory analysis part of SEM, the construct of latent variables fitted well with the data. Poly-drug use was significantly and directly affected by three predictors including monthly incomes (β = 0.09), friend drug use (β = 0.50), and ACEs (β = 0.11). The indirect effect of ACEs passing through self-perception of drugs (β = 0.09) was not significant.
ACEs have an independent and direct effect on the drug user for poly-drug use apart from the effect of drug-using friends and family income.
不良的童年经历（ACEs）与吸毒成年人多药物使用的风险增加有关。然而，关于 ACEs 与药物使用模式之间直接或间接关系的文献很少。因此，我们旨在通过结构方程模型（SEM）确定 ACEs 对成年人药物使用模式影响的途径。
2021 年，在中国西南地区的一家药物滥用诊所，通过受访者驱动抽样和连续抽样对成年吸毒者进行了一项横断面研究。使用 R 软件 4.2.1 进行描述性、单变量和 SEM 分析。
在从一家药物滥用诊所招募的 406 名参与者中，平均年龄为 34 岁。大多数参与者是少数民族（79.6%）的未婚男性患者（98.3%）和就业人员（81.2%）。近 95.5%的人经历过 ACEs，其中 46.6%的人报告经历过四种或更多 ACEs。自我感知药物滥用评分、朋友药物使用评分和药物使用评分的中位数分别为 8.0（3.0，11.0）、1.0（0.0，1.0）和 1.0（1.0，2.0）。在 SEM 的验证性分析部分，潜在变量的结构与数据拟合良好。多药物使用明显且直接受到三个预测因素的影响，包括月收入（β=0.09）、朋友药物使用（β=0.50）和 ACEs（β=0.11）。ACEs 通过自我感知药物（β=0.09）的间接效应不显著。
除了吸毒朋友和家庭收入的影响外，ACEs 对多药物使用者具有独立和直接的影响。
