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用于生物传感及应用的太赫兹超表面石墨烯研究进展

Advances in terahertz metasurface graphene for biosensing and application.

作者信息

Bi Hao, Yang Maosheng, You Rui

机构信息

Beijing Key Laboratory of Optoelectronic Measurement Technology, Beijing Information Science and Technology University, Beijing, China.

Beijing Advanced Innovation Center for Integrated Circuits, 100084, Beijing, China.

出版信息

Discov Nano. 2023 Apr 15;18(1):63. doi: 10.1186/s11671-023-03814-8. eCollection 2023 Dec.

DOI:10.1186/s11671-023-03814-8
PMID:37091985
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10105365/
Abstract

Based on the extraordinary electromagnetic properties of terahertz waves, such as broadband, low energy, high permeability, and biometric fingerprint spectra, terahertz sensors show great application prospects in the biochemical field. However, the sensitivity of terahertz sensing technology is increasingly required by modern sensing demands. With the development of terahertz technology and functional materials, graphene-based terahertz metasurface sensors with the advantages of high sensitivity, fingerprint identification, nondestructive and anti-interference are gradually gaining attention. In addition to providing ideas for terahertz biosensors, these devices have attracted in-depth research and development by scientists. An overview of graphene-based terahertz metasurfaces and their applications in the detection of biochemical molecules is presented. This includes sensor mechanism research, graphene metasurface index evaluation, protein and nucleic acid sensors, and other chemical molecule sensing. A comparative analysis of graphene, nanomaterials, silicon, and metals to develop material-integrated metasurfaces. Furthermore, a brief summary of the main performance results of this class of devices is presented, along with suggestions for improvements to the existing shortcoming.

摘要

基于太赫兹波的非凡电磁特性，如宽带、低能量、高渗透性和生物特征指纹光谱，太赫兹传感器在生化领域展现出巨大的应用前景。然而，现代传感需求对太赫兹传感技术的灵敏度要求越来越高。随着太赫兹技术和功能材料的发展，具有高灵敏度、指纹识别、无损和抗干扰等优点的基于石墨烯的太赫兹超表面传感器逐渐受到关注。这些器件除了为太赫兹生物传感器提供思路外，还吸引了科学家们的深入研发。本文综述了基于石墨烯的太赫兹超表面及其在生化分子检测中的应用。这包括传感器机理研究、石墨烯超表面折射率评估、蛋白质和核酸传感器以及其他化学分子传感。对石墨烯、纳米材料、硅和金属进行比较分析，以开发材料集成超表面。此外，还介绍了这类器件的主要性能结果，并针对现有缺点提出了改进建议。

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