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气道力学研究中肺音与气体潴留的比较。

Comparison of lung sounds and gas trapping in the study of airway mechanics.

作者信息

Frazer D G, Smith L D, Brancazio L R, Weber K C

出版信息

Environ Health Perspect. 1986 Apr;66:25-30. doi: 10.1289/ehp.866625.

Abstract

We have previously shown that gas is trapped in isolated animal lungs and have proposed that this gas-trapping process is related to meniscus formation in the small airways of the lung. The purpose of this investigation was to compare how the lung sound-generation process and the gas-trapping process are related to airway mechanics and each other. Rats were anesthetized, the heart and lungs were removed en bloc and placed in a liquid-filled plethysmograph. Lung sounds were recorded by using a microphone acoustically coupled to the tracheal cannula. The results show that discontinuous lung sounds in the form of crackles occur during lung inflation at the same time gas trapping takes place.

摘要

我们之前已经表明,气体被困在离体动物肺中,并提出这种气体捕获过程与肺小气道中半月板的形成有关。本研究的目的是比较肺音产生过程和气体捕获过程与气道力学之间的关系以及它们彼此之间的关系。将大鼠麻醉,将心脏和肺整体取出并置于充满液体的体积描记器中。通过与气管插管声学耦合的麦克风记录肺音。结果表明,在肺充气过程中,当气体捕获发生时,会出现以爆裂音形式出现的间断性肺音。

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本文引用的文献

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The effects of several gases (He, N2, N2O, and SF6) on gas trapping in excised lungs.
Respir Physiol. 1980 Jun;40(3):323-33. doi: 10.1016/0034-5687(80)90032-8.
2
Epidemiology of pulmonary lesions in nontextile and cotton textile workers: a retrospective autopsy analysis.
Arch Environ Health. 1980 May-Jun;35(3):133-8. doi: 10.1080/00039896.1980.10667480.
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Lung degassing: an evaluation of two methods.肺排气:两种方法的评估
J Appl Physiol Respir Environ Exerc Physiol. 1980 Feb;48(2):370-5. doi: 10.1152/jappl.1980.48.2.370.
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