Frazer D G, Smith L D, Brancazio L R, Weber K C
Environ Health Perspect. 1986 Apr;66:25-30. doi: 10.1289/ehp.866625.
We have previously shown that gas is trapped in isolated animal lungs and have proposed that this gas-trapping process is related to meniscus formation in the small airways of the lung. The purpose of this investigation was to compare how the lung sound-generation process and the gas-trapping process are related to airway mechanics and each other. Rats were anesthetized, the heart and lungs were removed en bloc and placed in a liquid-filled plethysmograph. Lung sounds were recorded by using a microphone acoustically coupled to the tracheal cannula. The results show that discontinuous lung sounds in the form of crackles occur during lung inflation at the same time gas trapping takes place.
我们之前已经表明,气体被困在离体动物肺中,并提出这种气体捕获过程与肺小气道中半月板的形成有关。本研究的目的是比较肺音产生过程和气体捕获过程与气道力学之间的关系以及它们彼此之间的关系。将大鼠麻醉,将心脏和肺整体取出并置于充满液体的体积描记器中。通过与气管插管声学耦合的麦克风记录肺音。结果表明,在肺充气过程中,当气体捕获发生时,会出现以爆裂音形式出现的间断性肺音。