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[预防痴呆症]

[Prevention of dementia].

作者信息

Schippinger Walter M, Pichler Gerald

机构信息

Abteilung für Innere Medizin, Albert-Schweitzer-Klinik, Geriatrische Gesundheitszentren der Stadt Graz, Albert-Schweitzer-Gasse 36, 8020, Graz, Österreich.

Abteilung für Neurologie, Albert-Schweitzer-Klinik, Geriatrische Gesundheitszentren der Stadt Graz, Graz, Österreich.

出版信息

Z Gerontol Geriatr. 2023 May;56(3):227-234. doi: 10.1007/s00391-023-02175-2. Epub 2023 Apr 25.

Abstract

With increasing life expectancy, the prevalence of dementia is increasing worldwide. Dementia is among the greatest challenges for healthcare and social systems of the future. Approximately 40% of newly diagnosed cases of dementia are associated with risk factors that can potentially be influenced by preventive measures. Based on the evidence from longitudinal studies, systematic reviews and meta-analyses, the Lancet commission on dementia prevention, intervention and care has defined 12 risk factors that are associated with an increased risk for dementia: low level of education, hearing impairment, traumatic brain injury, arterial hypertension, diabetes mellitus, smoking, excessive alcohol consumption, depression, obesity, social isolation, and air pollution.

摘要

随着预期寿命的增加,痴呆症在全球的患病率正在上升。痴呆症是未来医疗保健和社会系统面临的最大挑战之一。新诊断出的痴呆症病例中约40%与风险因素相关,这些风险因素有可能通过预防措施加以影响。基于纵向研究、系统评价和荟萃分析的证据,《柳叶刀》痴呆症预防、干预和护理委员会确定了12个与痴呆症风险增加相关的风险因素:低教育水平、听力障碍、创伤性脑损伤、动脉高血压、糖尿病、吸烟、过量饮酒、抑郁症、肥胖、社会隔离和空气污染。

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