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猫的晕动病反射弧绕过最后区。

Motion sickness reflex arc bypasses the area postrema in cats.

作者信息

Borison H L, Borison R

出版信息

Exp Neurol. 1986 Jun;92(3):723-37. doi: 10.1016/0014-4886(86)90312-2.

DOI:10.1016/0014-4886(86)90312-2
PMID:3709744
Abstract

Motion-induced vomiting was studied in cats exposed to vertical sinusoidal oscillation on a spring-suspended platform. Two groups of five cats each, namely, motion-untested and motion sickness-susceptible, were subjected to chronic ablation of the area postrema. Motion sickness occurred postoperatively in all the previously untested cats, and in four of the five previously susceptible cats. Statistical comparison with normal cats indicated that the operated cats were significantly more susceptible to motion sickness. The manifest loss of susceptibility in one cat with a lesion is attributed to excessive peripostremal damage. It is concluded from these results that the area postrema is not an essential link in the reflex arc of motion-induced vomiting.

摘要

在置于弹簧悬挂平台上并暴露于垂直正弦振荡的猫身上研究了运动诱发的呕吐。两组猫,每组五只,分别为未经运动测试的和易患晕动病的,均接受了最后区的慢性切除。术后,所有先前未经测试的猫以及五只先前易患晕动病的猫中的四只都出现了晕动病。与正常猫的统计比较表明,接受手术的猫对晕动病的易感性明显更高。一只患有损伤的猫易感性明显丧失归因于最后区周围的过度损伤。从这些结果得出的结论是,最后区不是运动诱发呕吐反射弧中的必要环节。

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