School of Science, Zhejiang University of Science and Technology, Hangzhou, 310023, China.
School of Mathematics and Statistics, Shaanxi Normal University, Xi'an, 710062, China.
J Math Biol. 2023 Apr 25;86(5):81. doi: 10.1007/s00285-023-01916-6.
We incorporate the disease state and testing state into the formulation of a COVID-19 epidemic model. For this model, the basic reproduction number is identified and its dependence on model parameters related to the testing process and isolation efficacy is discussed. The relations between the basic reproduction number, the final epidemic and peak sizes, and the model parameters are further explored numerically. We find that fast test reporting does not always benefit the control of the COVID-19 epidemic if good quarantine while awaiting test results is implemented. Moreover, the final epidemic and peak sizes do not always increase along with the basic reproduction number. Under some circumstances, lowering the basic reproduction number increases the final epidemic and peak sizes. Our findings suggest that properly implementing isolation for individuals who are waiting for their testing results would lower the basic reproduction number as well as the final epidemic and peak sizes.
我们将疾病状态和检测状态纳入 COVID-19 传染病模型的制定中。对于该模型,我们确定了基本再生数,并讨论了其对与检测过程和隔离效果相关的模型参数的依赖性。进一步通过数值方法探讨了基本再生数、最终疫情和高峰期规模以及模型参数之间的关系。我们发现,如果在等待检测结果时实施良好的隔离措施,快速报告检测结果并不总是有利于控制 COVID-19 疫情。此外,最终疫情和高峰期规模并不总是随着基本再生数的增加而增加。在某些情况下,降低基本再生数会增加最终疫情和高峰期规模。我们的研究结果表明,对于那些正在等待检测结果的个体,适当实施隔离措施将降低基本再生数以及最终疫情和高峰期规模。