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兔跟腱撕脱模型中各种修复技术的体外生物力学评估:聚己内酯板的应用

Ex Vivo Biomechanical Assessment of Various Repair Techniques in a Rabbit Calcaneal Tendon Avulsion Model: Application of Polycaprolactone Plate.

作者信息

Huidan Zheng, Kang Jinsu, Kim Namsoo, Heo Suyoung

机构信息

Department of Veterinary Surgery, College of Veterinary Medicine, Jeonbuk National University, 79 Gobong-ro, Iksan 54596, Republic of Korea.

出版信息

Vet Sci. 2023 Apr 12;10(4):289. doi: 10.3390/vetsci10040289.

DOI:10.3390/vetsci10040289
PMID:37104444
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10146963/
Abstract

This study was aimed at evaluating the biomechanical properties and gapping characteristics of tendon repair methods using a combination of a three-loop pulley (3LP) pattern, a titanium plate, and a polycaprolactone (PCL) plate in a rabbit gastrocnemius tendon (GT) model ( = 50). GTs were randomly assigned to five groups ( = 10/group). Transected GTs were repaired with a 3LP pattern alone or in conjunction with an epitendinous suture (ES), a 5-hole 1 mm PCL plate, a 5-hole 2 mm PCL plate, or a 5-hole 1.5 mm titanium plate. The yield, peak, and failure force, as well as the occurrence and force of 1-mm and 3-mm gapping were examined. The mean yield, peak, and failure force of the 3LP + titanium plate group were higher than that of other groups. The biomechanical properties of a 3LP + a 2 mm PCL plate were similar to 3LP + ES constructs in this model. In all specimens in all groups, 1 mm gap formation was observed. The frequency of 3 mm gap formation was 70% and 90% in the 3LP + 2 mm PCL plate group and the 3LP + 1.5 mm titanium plate group, respectively. Additional studies evaluating PCL plates to determine the effect on the healing and blood supply of tendon are needed.

摘要

本研究旨在使用三环滑轮(3LP)模式、钛板和聚己内酯(PCL)板的组合,在兔腓肠肌腱(GT)模型(n = 50)中评估肌腱修复方法的生物力学特性和间隙特征。GT被随机分为五组(每组n = 10)。横断的GT分别采用单独的3LP模式或与腱周缝合(ES)、5孔1 mm PCL板、5孔2 mm PCL板或5孔1.5 mm钛板联合修复。检测屈服力、峰值力和破坏力,以及1 mm和3 mm间隙的出现情况和间隙力。3LP +钛板组的平均屈服力、峰值力和破坏力高于其他组。在该模型中,3LP + 2 mm PCL板的生物力学特性与3LP + ES结构相似。在所有组的所有标本中,均观察到1 mm间隙形成。3LP + 2 mm PCL板组和3LP + 1.5 mm钛板组中3 mm间隙形成的频率分别为70%和90%。需要进一步评估PCL板以确定其对肌腱愈合和血供的影响的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9bb/10146963/012099498937/vetsci-10-00289-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9bb/10146963/5e507f0741f4/vetsci-10-00289-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9bb/10146963/ff5b07d3e88f/vetsci-10-00289-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9bb/10146963/012099498937/vetsci-10-00289-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9bb/10146963/5e507f0741f4/vetsci-10-00289-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9bb/10146963/ff5b07d3e88f/vetsci-10-00289-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9bb/10146963/012099498937/vetsci-10-00289-g003.jpg

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本文引用的文献

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Am J Vet Res. 2022 Jan 28;83(4):305-311. doi: 10.2460/ajvr.21.07.0088.
2
Ex vivo mechanical testing of various suture patterns for use in tendon plating.各种用于肌腱板的缝线模式的体外机械测试。
Vet Surg. 2021 Aug;50(6):1296-1303. doi: 10.1111/vsu.13659. Epub 2021 Jun 2.
3
Biomechanical evaluation of an autologous flexor digitorum lateralis graft to augment the surgical repair of gastrocnemius tendon laceration in a canine ex vivo model.
自体指浅屈肌移植修复犬跟腱撕裂的生物力学评估:一种在体实验模型。
Vet Surg. 2020 Dec;49(8):1545-1554. doi: 10.1111/vsu.13453. Epub 2020 Jun 14.
4
Surgical outcomes and complications of septal extension graft supported by 3D printed polycaprolactone plate.3D 打印聚己内酯板支撑鼻中隔延伸移植物的手术效果和并发症。
Laryngoscope. 2020 Jul;130(7):1680-1685. doi: 10.1002/lary.28436. Epub 2019 Nov 27.
5
Effect of bite depth of an epitendinous suture on the biomechanical strength of repaired canine flexor tendons.腱周缝线的缝合深度对修复犬屈肌腱生物力学强度的影响。
Am J Vet Res. 2019 Nov;80(11):1043-1049. doi: 10.2460/ajvr.80.11.1043.
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Effect of a continuous epitendinous suture as adjunct to three-loop pulley and locking-loop patterns for flexor tendon repair in a canine model.在犬类模型中,连续腱周缝合作为三袢滑车和锁定环缝合法辅助手段用于屈肌腱修复的效果。
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