免疫印记：了解 COVID-19。
Immunological imprinting: Understanding COVID-19.
机构信息
Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.
Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA; Center for Vaccines and Immunity to Microbial Pathogens, Washington University School of Medicine, St. Louis, MO, USA; The Andrew M. and Jane M. Bursky Center for Human Immunology & Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO, USA.
出版信息
Immunity. 2023 May 9;56(5):909-913. doi: 10.1016/j.immuni.2023.04.012. Epub 2023 Apr 19.
Immunological imprinting generically refers to the effects prior exposures have on subsequent immune responses to, and eventually protection against, antigenically related viruses. Here, Koutsakos and Ellebedy explain different concepts and terms around imprinting and the fundamental immunological principles behind it. They also discuss the potential role imprinting may have in the context of COVID-19 vaccines.
免疫印迹通常是指先前暴露对随后针对抗原相关病毒的免疫反应和最终保护的影响。在这里，Koutsakos 和 Ellebedy 解释了印迹及其背后的基本免疫学原理的不同概念和术语。他们还讨论了印迹在 COVID-19 疫苗背景下可能发挥的作用。
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