Reiter's disease can no longer be considered a rare and relatively benign syndrome consisting of the clinical triad of urethritis, conjunctivitis and arthritis. It is, in fact, a post-infectious reactive arthritis that belongs to a new group of diseases now called seronegative spondyloarthropathies. These diseases are characterized by an extremely high association with the genetic marker, human leukocyte antigen B27. In its full course, the disease often is incomplete with its initial clinical manifestations and characterized by chronicity and progressive crippling recurrences.
赖特综合征不再被视为一种罕见且相对良性的综合征，该综合征由尿道炎、结膜炎和关节炎这一临床三联征组成。事实上，它是一种感染后反应性关节炎，属于现在被称为血清阴性脊柱关节病的一组新疾病。这些疾病的特点是与遗传标记人类白细胞抗原B27高度相关。在疾病的整个过程中，其初始临床表现往往并不完全，且具有慢性和进行性致残复发的特点。
