Neuwelt C M, Borenstein D G, Jacobs R P
J Rheumatol. 1982 Mar-Apr;9(2):268-72.
A diagnosis of Reiter's syndrome was made in 12 males and 13 females based on an asymmetrical oligoarthritis with lower extremity predominance and at least 1 characteristic extraarticular manifestation. The pattern of disease was similar in both sexes; females had more extensive upper extremity joint involvement and ocular inflammation; males had more nonbacterial urethritis. Eighty-two % of males and 62% of females were HLA-B27 positive. We suggest that Reiter's syndrome has not been diagnosed in more females in the past because of an historical bias, a reliance on the complete classical triad, and confusion with seronegative rheumatoid arthritis.
基于以下症状对12名男性和13名女性做出了赖特综合征的诊断：不对称性少关节炎，以下肢为主，且至少有1种特征性关节外表现。男女的疾病模式相似；女性上肢关节受累范围更广且有眼部炎症；男性有更多非细菌性尿道炎。82%的男性和62%的女性HLA - B27呈阳性。我们认为，过去赖特综合征在更多女性中未被诊断出来是由于历史偏见、对完整经典三联征的依赖以及与血清阴性类风湿关节炎的混淆。
