Programa de Pós-Graduação em Biotecnologia Vegetal e Bioprocessos, Centro de Ciências em Saúde, Universidade Federal do Rio de Janeiro, Rio de Janeiro CEP 21941-590, Brazil.
Programa de Pós-Graduação em Higiene Veterinária e Processamento Tecnológico de Produtos de Origem Animal, Faculdade de Veterinária, Universidade Federal Fluminense, Niterói, Rio de Janeiro CEP 24220-000, Brazil.
Molecules. 2023 Apr 13;28(8):3437. doi: 10.3390/molecules28083437.
The genus, the etiological agent of aspergillosis, is an important food contaminant and mycotoxin producer. Plant extracts and essential oils are a source of bioactive substances with antimicrobial potential that can be used instead of synthetic food preservatives. Species from the Lauraceae family and the genus have been used as traditional medicinal herbs. Their essential oils can be nanoemulsified to enhance their stability and bioavailability and increase their use. Therefore, this study sought to prepare and characterize both nanoemulsion and essential oil from the 's leaves, a native and endemic species from the Mata Atlântica forest in Brazil, and evaluate the activity against RC 2054, NRRL 2999, and NRRL 3174. The products were added to Sabouraud Dextrose Agar at concentrations of 256, 512, 1024, 2048, and 4096 µg/mL. The strains were inoculated and incubated for up to 96 h with two daily measurements. The results did not show fungicidal activity under these conditions. A fungistatic effect, however, was observed. The nanoemulsion decreased the fungistatic concentration of the essential oil more than ten times, mainly in . There were no significant changes in aflatoxin production.
该属是曲霉菌病的病原体,是一种重要的食物污染物和霉菌毒素产生菌。植物提取物和精油是具有抗菌潜力的生物活性物质的来源,可以替代合成的食品防腐剂。樟科和该属的一些物种被用作传统草药。它们的精油可以被纳米乳化以提高其稳定性和生物利用度,并增加其用途。因此,本研究旨在制备和表征来自巴西大西洋森林本土和特有物种的 's 叶子的纳米乳液和精油,并评估其对 RC 2054、NRRL 2999 和 NRRL 3174 的活性。将产物以 256、512、1024、2048 和 4096 µg/mL 的浓度添加到沙氏葡萄糖琼脂中。接种菌株并在 96 小时内每天测量两次进行孵育。在这些条件下,未显示出杀菌活性。然而,观察到了抑菌作用。纳米乳液使精油的抑菌浓度降低了十倍以上,主要是在. 黄曲霉毒素的产生没有显著变化。