School of Nursing, Sun Yat-sen University, Guangzhou 510006, China.
Department of Gastric Surgery, Department of General Surgery, Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510006, China.
Nutrients. 2023 Apr 13;15(8):1883. doi: 10.3390/nu15081883.
(1) Background: A major challenge for post-discharged gastric cancer patients following gastrectomy is the impact of the anatomy change on decreased oral intake, nutritional status, and, ultimately, quality of life. The purpose of this study is to examine the feasibility and preliminary effects of an individualized mHealth nutrition (iNutrition) intervention in post-discharged gastric cancer patients following gastrectomy. (2) Methods: A mixed-method feasibility study with a parallel randomized controlled design was conducted. Patients were randomly assigned to either the iNutrition intervention group ( = 12) or the control group ( = 12). Participants completed measures at baseline (T0), four (T1), and twelve weeks (T2) post-randomization. (3) Results: Recruitment (33%) and retention (87.5%) rates along with high adherence and acceptability supported the feasibility of the iNutrition intervention for post-discharged gastric cancer patients following gastrectomy, echoed by the qualitative findings. The iNutrition intervention significantly improved participants' nutritional behavior ( = 0.005), energy intake ( = 0.038), compliance with energy requirements ( = 0.006), and compliance with protein requirements ( = 0.008). (4) Conclusions: The iNutrition intervention is feasible and potentially benefits post-discharged gastric cancer patients following gastrectomy. A larger trial is required to establish the efficacy of this approach. Trial Registration: 19 October 2022 Chinese Clinical Trial Registry, ChiCTR2200064807.
(1) 背景：胃切除术后出院的胃癌患者面临的主要挑战是解剖结构改变对口服摄入量、营养状况的影响，最终影响生活质量。本研究旨在探讨个体化移动医疗营养（iNutrition）干预对胃切除术后出院的胃癌患者的可行性和初步效果。
(2) 方法：采用混合方法可行性研究，平行随机对照设计。患者随机分为 iNutrition 干预组（n = 12）和对照组（n = 12）。参与者在基线（T0）、4 周（T1）和 12 周（T2）时完成测量。
(3) 结果：招募（33%）和保留（87.5%）率以及高依从性和可接受性支持了 iNutrition 干预对胃切除术后出院的胃癌患者的可行性，定性研究结果也证实了这一点。iNutrition 干预显著改善了参与者的营养行为（ = 0.005）、能量摄入（ = 0.038）、能量需求的依从性（ = 0.006）和蛋白质需求的依从性（ = 0.008）。
(4) 结论：iNutrition 干预是可行的，可能对胃切除术后出院的胃癌患者有益。需要更大规模的试验来确定这种方法的疗效。试验注册：2022 年 10 月 19 日，中国临床试验注册中心，ChiCTR2200064807。
