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Buprenorphine involvement in opioid overdose deaths: A retrospective analysis of postmortem toxicology in Marion County, Indiana, 2015-2021.丁丙诺啡与阿片类药物过量死亡的关系:对2015 - 2021年印第安纳州马里恩县尸检毒理学的回顾性分析。
Drug Alcohol Depend Rep. 2023 Mar;6. doi: 10.1016/j.dadr.2023.100131. Epub 2023 Jan 4.
2
Prior authorization restrictions on medications for opioid use disorder: trends in state laws from 2005 to 2019.阿片类药物使用障碍治疗药物的预先授权限制:2005 年至 2019 年各州法律的趋势。
Ann Med. 2023 Dec;55(1):514-520. doi: 10.1080/07853890.2023.2171107.
3
Demographic and socioeconomic correlates to buprenorphine access in pharmacies.药房中丁丙诺啡获取情况的人口统计学和社会经济相关因素。
J Am Pharm Assoc (2003). 2023 May-Jun;63(3):751-759. doi: 10.1016/j.japh.2022.12.015. Epub 2022 Dec 16.
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Cost-effectiveness of office-based buprenorphine treatment for opioid use disorder.基于办公室的丁丙诺啡治疗阿片类药物使用障碍的成本效益。
Drug Alcohol Depend. 2023 Feb 1;243:109762. doi: 10.1016/j.drugalcdep.2022.109762. Epub 2022 Dec 30.
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Availability of medications for opioid use disorder in outpatient and inpatient pharmacies in South Florida: a secret shopper survey.南佛罗里达州门诊和住院药房阿片类药物使用障碍药物的供应情况:秘密购物者调查。
Addict Sci Clin Pract. 2022 Nov 18;17(1):63. doi: 10.1186/s13722-022-00346-x.
6
Total cost of care associated with opioid use disorder treatment.与阿片类药物使用障碍治疗相关的总医疗费用。
Prev Med. 2023 Jan;166:107345. doi: 10.1016/j.ypmed.2022.107345. Epub 2022 Nov 10.
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Coverage and Prior Authorization Policies for Medications for Opioid Use Disorder in Medicaid Managed Care.医疗补助管理式医疗中阿片类药物使用障碍药物的覆盖范围和事先授权政策。
JAMA Health Forum. 2022 Nov 4;3(11):e224001. doi: 10.1001/jamahealthforum.2022.4001.
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Trends in Buprenorphine Coverage and Prior Authorization Requirements in US Commercial Formularies, 2017-2021.2017-2021 年美国商业处方集中美沙酮覆盖范围和事先授权要求的趋势。
JAMA Health Forum. 2022 Jul 8;3(7):e221821. doi: 10.1001/jamahealthforum.2022.1821. eCollection 2022 Jul.
9
Has the treatment gap for opioid use disorder narrowed in the U.S.?: A yearly assessment from 2010 to 2019".美国阿片类药物使用障碍的治疗差距是否缩小了?2010 年至 2019 年的年度评估。
Int J Drug Policy. 2022 Dec;110:103786. doi: 10.1016/j.drugpo.2022.103786. Epub 2022 Aug 4.
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Rural community pharmacist willingness to dispense Suboxone® - A secret shopper investigation in South-Central Appalachia.农村社区药剂师配发舒泊西汀(Suboxone®)的意愿——美国中阿巴拉契亚地区的一项暗访调查
Explor Res Clin Soc Pharm. 2021 Oct 23;4:100082. doi: 10.1016/j.rcsop.2021.100082. eCollection 2021 Dec.

美沙酮类物质使用障碍的丁丙诺啡治疗:2017-21 年保险限制的比较。

Buprenorphine Treatment For Opioid Use Disorder: Comparison Of Insurance Restrictions, 2017-21.

机构信息

Barbara Andraka-Christou (

Kosali I. Simon, Indiana University, Bloomington, Indiana.

出版信息

Health Aff (Millwood). 2023 May;42(5):658-664. doi: 10.1377/hlthaff.2022.01513.

DOI:10.1377/hlthaff.2022.01513
PMID:37126752
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10275692/
Abstract

Buprenorphine is a treatment medication that decreases mortality risks among people with opioid use disorder (OUD). Despite its efficacy, buprenorphine is underused in the US. Insurance restrictions are commonly cited as barriers to buprenorphine prescribing. Using Medicaid, Medicare Advantage, and commercial insurance formulary files, we examined insurance-imposed utilization restrictions for buprenorphine for OUD for each year from 2017 to 2021 by insurance type. Almost all plans covered immediate-release buprenorphine in 2021, with a general trend of decreasing prior authorization requirements and quantity limits since 2017. In contrast, two payers had relatively low coverage of extended-release buprenorphine, with only 46 percent of commercial plans and only 19 percent of Medicare Advantage plans covering this formulation. Even though most Medicaid plans covered extended-release buprenorphine in 2021, 37 percent required prior authorization. Policy makers and researchers concerned with buprenorphine insurance barriers should shift their attention to extended-release buprenorphine. State lawmakers could help address these barriers by mandating that insurers include extended-release buprenorphine on their preferred drug lists.

摘要

丁丙诺啡是一种治疗药物,可降低阿片类药物使用障碍(OUD)患者的死亡率。尽管丁丙诺啡有效,但在美国的使用不足。保险限制通常被认为是开具丁丙诺啡处方的障碍。我们使用医疗补助、医疗保险优势和商业保险处方集文件,按保险类型检查了 2017 年至 2021 年每年 OUD 丁丙诺啡的保险规定的使用限制。几乎所有计划在 2021 年均涵盖速释丁丙诺啡,自 2017 年以来,事先授权要求和数量限制呈下降趋势。相比之下,有两个支付者对丁丙诺啡的控释制剂的覆盖范围相对较低,只有 46%的商业计划和 19%的医疗保险优势计划涵盖这种配方。尽管大多数医疗补助计划在 2021 年涵盖了丁丙诺啡的控释制剂,但仍有 37%需要事先授权。关注丁丙诺啡保险障碍的政策制定者和研究人员应将注意力转向丁丙诺啡的控释制剂。州议员可以通过要求保险公司将丁丙诺啡的控释制剂列入其首选药物清单来帮助解决这些障碍。