妊娠期糖尿病和围产期产妇抑郁与儿童早期行为问题的关联：儿童健康结局的环境影响（ECHO）研究。
Association of Gestational Diabetes Mellitus and Perinatal Maternal Depression with Early Childhood Behavioral Problems: An Environmental Influences on Child Health Outcomes (ECHO) Study.
机构信息
Department of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons, New York, New York, USA.
Department of Psychology, University of Southern California, Los Angeles, California, USA.
出版信息
Child Dev. 2023 Nov-Dec;94(6):1595-1609. doi: 10.1111/cdev.13938. Epub 2023 May 2.
This study examined the association of gestational diabetes mellitus (GDM), prenatal, and postnatal maternal depressive symptoms with externalizing, internalizing, and autism spectrum problems on the Preschool Child Behavior Checklist in 2379 children aged 4.12 ± 0.60 (48% female; 47% White, 32% Black, 15% Mixed Race, 4% Asian, <2% American Indian/Alaskan Native, <2% Native Hawaiian; 23% Hispanic). Data were collected from the NIH Environmental influences on Child Health Outcomes (ECHO) Program from 2009-2021. GDM, prenatal, and postnatal maternal depressive symptoms were each associated with increased child externalizing and internalizing problems. GDM was associated with increased autism behaviors only among children exposed to perinatal maternal depressive symptoms above the median level. Stratified analyses revealed a relation between GDM and child outcomes in males only.
本研究调查了 2379 名年龄为 4.12±0.60 岁的儿童（48%为女性；47%为白人，32%为黑人，15%为混合族裔，4%为亚洲人，<2%为美洲印第安人/阿拉斯加原住民，<2%为夏威夷原住民；23%为西班牙裔）在幼儿行为检查表上的外化、内化和自闭症谱系问题与妊娠期糖尿病（GDM）、产前和产后母亲抑郁症状之间的关联。这些数据来自于 2009-2021 年 NIH 环境对儿童健康结果的影响（ECHO）计划。GDM、产前和产后母亲抑郁症状均与儿童的外化和内化问题增加有关。只有在暴露于中值以上围产期母亲抑郁症状的儿童中，GDM 才与自闭症行为增加有关。分层分析显示，GDM 与男性儿童的结果之间存在关系。
Zotero 插件