重症监护病房中重症医师与患者的比例与死亡率。

Intensivist physician-to-patient ratios and mortality in the intensive care unit.

机构信息

CRISMA Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, 602B Allan Magee Scaife Hall, 3550 Terrace Street, Pittsburgh, PA, 15213, USA.

Department of Health Policy and Management, University of Pittsburgh School of Public Health, Pittsburgh, PA, 15213, USA.

出版信息

Intensive Care Med. 2023 May;49(5):545-553. doi: 10.1007/s00134-023-07066-z. Epub 2023 May 3.

Abstract

PURPOSE

A high daily census may hinder the ability of physicians to deliver quality care in the intensive care unit (ICU). We sought to determine the relationship between intensivist-to-patient ratios and mortality among ICU patients.

METHODS

We performed a retrospective cohort study of intensivist-to-patient ratios in 29 ICUs in 10 hospitals in the United States from 2018 to 2020. We used meta-data from progress notes in the electronic health record to determine an intensivist-specific caseload for each ICU day. We then fit a multivariable proportional hazards model with time-varying covariates to estimate the relationship between the daily intensivist-to-patient ratio and ICU mortality at 28 days.

RESULTS

The final analysis included 51,656 patients, 210,698 patient days, and 248 intensivist physicians. The average caseload per day was 11.8 (standard deviation: 5.7). There was no association between the intensivist-to-patient ratio and mortality (hazard ratio for each additional patient: 0.987, 95% confidence interval: 0.968-1.007, p = 0.2). This relationship persisted when we defined the ratio as caseload over the sample-wide average (hazard ratio: 0.907, 95% confidence interval: 0.763-1.077, p = 0.26) and cumulative days with a caseload over the sample-wide average (hazard ratio: 0.991, 95% confidence interval: 0.966-1.018, p = 0.52). The relationship was not modified by the presence of physicians-in-training, nurse practitioners, and physician assistants (p value for interaction term: 0.14).

CONCLUSIONS

Mortality for ICU patients appears resistant to high intensivist caseloads. These results may not generalize to ICUs organized differently than those in this sample, such as ICUs outside the United States.

摘要

目的

高的日住院人数可能会阻碍重症监护病房(ICU)医生提供高质量护理的能力。我们试图确定 ICU 患者的重症监护医师与患者比例与死亡率之间的关系。

方法

我们对 2018 年至 2020 年期间美国 10 家医院的 29 个 ICU 的重症监护医师与患者比例进行了回顾性队列研究。我们使用电子病历中的进度记录中的元数据来确定每个 ICU 日的特定重症监护医师病例数。然后,我们使用具有时变协变量的多变量比例风险模型来估计 ICU 死亡率在 28 天时的每日重症监护医师与患者比例之间的关系。

结果

最终分析包括 51656 名患者、210698 个患者日和 248 名重症监护医师。平均每日工作量为 11.8(标准差:5.7)。重症监护医师与患者比例与死亡率之间没有关联(每增加一名患者的风险比:0.987,95%置信区间:0.968-1.007,p=0.2)。当我们将该比例定义为样本范围内平均工作量的病例数(风险比:0.907,95%置信区间:0.763-1.077,p=0.26)和超过样本范围内平均工作量的累计天数(风险比:0.991,95%置信区间:0.966-1.018,p=0.52)时,这种关系仍然存在。这种关系不受住院医师、执业护士和医师助理存在的影响(交互项 p 值:0.14)。

结论

对于 ICU 患者,死亡率似乎不受高重症监护医师工作量的影响。这些结果可能不适用于与本样本不同组织的 ICU,例如美国以外的 ICU。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ae3/10155655/8f10b9df64ec/134_2023_7066_Fig1_HTML.jpg

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