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Gut microbiota as a potential key to modulating humoral immunogenicity of new platform COVID-19 vaccines.

作者信息

Seong Hye, Choi Bo Kyu, Han Young-Hee, Kim Jun Hyoung, Gim Jeong-An, Lim Sooyeon, Noh Ji Yun, Cheong Hee Jin, Kim Woo Joo, Song Joon Young

机构信息

Department of Internal Medicine, Korea University College of Medicine, Seoul, Republic of Korea.

Asia Pacific Influenza Institute, Korea University College of Medicine, Seoul, Republic of Korea.

出版信息

Signal Transduct Target Ther. 2023 May 3;8(1):178. doi: 10.1038/s41392-023-01445-0.

DOI:10.1038/s41392-023-01445-0
PMID:37137906
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10154741/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e842/10156652/230bdec9e511/41392_2023_1445_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e842/10156652/230bdec9e511/41392_2023_1445_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e842/10156652/230bdec9e511/41392_2023_1445_Fig1_HTML.jpg

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Front Immunol. 2022 Jun 16;13:805881. doi: 10.3389/fimmu.2022.805881. eCollection 2022.
2
Modulation of immune responses to vaccination by the microbiota: implications and potential mechanisms.肠道菌群对疫苗免疫应答的调节作用：意义和潜在机制。
Nat Rev Immunol. 2022 Jan;22(1):33-46. doi: 10.1038/s41577-021-00554-7. Epub 2021 May 17.
3
The Impact of the Microbiome on Immunity to Vaccination in Humans.
猪的鼻腔和直肠微生物群参与了对副猪嗜血杆菌的抗体反应。
Sci Rep. 2025 Jan 17;15(1):2347. doi: 10.1038/s41598-025-85867-6.
4
Impact of an intranasal L-DBF vaccine on the gut microbiota in young and elderly mice.鼻腔内给予 L-DBF 疫苗对年轻和老年小鼠肠道微生物群的影响。
Gut Microbes. 2024 Jan-Dec;16(1):2426619. doi: 10.1080/19490976.2024.2426619. Epub 2024 Nov 9.
5
The gut microbiota modifies antibody durability and booster responses after SARS-CoV-2 vaccination.肠道微生物群改变了 SARS-CoV-2 疫苗接种后的抗体持久性和加强反应。
J Transl Med. 2024 Sep 6;22(1):827. doi: 10.1186/s12967-024-05637-2.
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Vaccines (Basel). 2024 Aug 14;12(8):916. doi: 10.3390/vaccines12080916.
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