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感染和未感染HIV患者中与牙周炎相关的因素

Factors Associated with Periodontitis in Patients with and without HIV.

作者信息

Pereira Luanderson Lopes, Veiga Siqueira Amorim Daniele, Brito Sampaio Willian, Almeida Cruz Azevêdo Thais, Bispo Pereira Cardoso Vanessa, Barreto Lemos Felipe, Silva Chang Andressa, Machado Fernanda, Pereira Lima Fernanda, Sampaio Neves Frederico, Leal Figueiredo Andreia Cristina

机构信息

Postgraduate Program in Dentistry and Health, Federal University of Bahia (UFBA), Salvador, Brazil.

Department of Pediatric Oncology, Barretos Cancer Hospital, São Paulo, Brazil.

出版信息

Int J Dent. 2023 Apr 29;2023:9929835. doi: 10.1155/2023/9929835. eCollection 2023.

Abstract

PURPOSE

The aim of this study was to compare clinical periodontal conditions in HIV-positive people on HAART with an HIV-negative group, in addition to investigating factors associated with periodontitis in the entire sample.

METHODS

This was a cross-sectional study. Data were collected by oral clinical examination for the diagnosis of periodontitis, review of medical records, and application of a questionnaire containing personal data, deleterious habits, and oral hygiene habits for the other variables. The results were analyzed by Pearson's test and Student's -test. A logistic regression model was constructed for the multivariate analysis and periodontitis was defined as a dependent variable. The analysis was performed on the entire sample (HIV+ and HIV-) and also on the group consisting of only people living with HIV.

RESULTS

Individuals older than 43 years old and with HIV were more likely to develop moderate and severe periodontitis (47.80 and 4.84 times, respectively). When analyzing only HIV+, in addition to age (OR = 2.795; CI = 1.080-7.233), the use of nonnucleoside reverse transcriptase inhibitors (NNRTIs) (OR = 2.841; CI = 1.135-7.112) was also associated with moderate and severe periodontitis.

CONCLUSION

It was possible to observe a higher prevalence of periodontitis among individuals with HIV, showing an association between the virus, advanced age, and moderate or severe periodontitis.

摘要

目的

本研究旨在比较接受高效抗逆转录病毒治疗(HAART)的HIV阳性人群与HIV阴性人群的临床牙周状况,并调查整个样本中与牙周炎相关的因素。

方法

这是一项横断面研究。通过口腔临床检查以诊断牙周炎、查阅病历,并应用一份包含个人数据、有害习惯和其他变量的口腔卫生习惯的问卷来收集数据。结果通过Pearson检验和Student's t检验进行分析。构建逻辑回归模型进行多变量分析,并将牙周炎定义为因变量。分析在整个样本(HIV阳性和HIV阴性)以及仅由HIV感染者组成的组中进行。

结果

43岁以上的HIV感染者更有可能患中度和重度牙周炎(分别为47.80倍和4.84倍)。仅分析HIV阳性者时,除年龄外(优势比[OR]=2.795;可信区间[CI]=1.080 - 7.233),使用非核苷类逆转录酶抑制剂(NNRTIs)(OR = 2.841;CI = 1.135 - 7.112)也与中度和重度牙周炎相关。

结论

可以观察到HIV感染者中牙周炎的患病率较高,表明病毒、高龄与中度或重度牙周炎之间存在关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e38/10163962/c31c70fd847d/IJD2023-9929835.001.jpg

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