Shaver Timothy B, Youner Emily, Goodman Joseph F, Samankan Shabnam
Otolaryngology - Head and Neck Surgery, George Washington University School of Medicine and Health Sciences, Washington, USA.
Pathology, George Washington University School of Medicine and Health Sciences, Washington, USA.
Cureus. 2023 Apr 6;15(4):e37206. doi: 10.7759/cureus.37206. eCollection 2023 Apr.
Carcinosarcoma is an uncommon tumor consisting of malignant epithelial and mesenchymal elements. Salivary gland carcinosarcoma is aggressive in nature, and given its biphasic histologic appearance, it has the potential to be mistaken for a less concerning entity. Intraoral minor salivary gland carcinosarcoma is exceedingly rare with the palate being the site most frequently involved. Only two cases of carcinosarcoma arising from the floor of the mouth (FOM) have been reported. We present a case of a non-healing FOM ulcer that was identified as a minor salivary gland carcinosarcoma on surgical pathology along with the steps and importance of accurate diagnosis.
癌肉瘤是一种罕见的肿瘤,由恶性上皮和间充质成分组成。涎腺癌肉瘤本质上具有侵袭性,鉴于其双相组织学表现,它有可能被误诊为病情较轻的疾病。口腔内小涎腺癌肉瘤极为罕见,腭部是最常受累的部位。仅报告过两例起源于口底(FOM)的癌肉瘤病例。我们报告一例不愈合的口底溃疡病例,经手术病理确诊为小涎腺癌肉瘤,并阐述准确诊断的步骤及重要性。