• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

口腔底部小唾液腺癌肉瘤

Minor Salivary Gland Carcinosarcoma of the Floor of the Mouth.

作者信息

Shaver Timothy B, Youner Emily, Goodman Joseph F, Samankan Shabnam

机构信息

Otolaryngology - Head and Neck Surgery, George Washington University School of Medicine and Health Sciences, Washington, USA.

Pathology, George Washington University School of Medicine and Health Sciences, Washington, USA.

出版信息

Cureus. 2023 Apr 6;15(4):e37206. doi: 10.7759/cureus.37206. eCollection 2023 Apr.

DOI:10.7759/cureus.37206
PMID:37159765
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10163846/
Abstract

Carcinosarcoma is an uncommon tumor consisting of malignant epithelial and mesenchymal elements. Salivary gland carcinosarcoma is aggressive in nature, and given its biphasic histologic appearance, it has the potential to be mistaken for a less concerning entity. Intraoral minor salivary gland carcinosarcoma is exceedingly rare with the palate being the site most frequently involved. Only two cases of carcinosarcoma arising from the floor of the mouth (FOM) have been reported. We present a case of a non-healing FOM ulcer that was identified as a minor salivary gland carcinosarcoma on surgical pathology along with the steps and importance of accurate diagnosis.

摘要

癌肉瘤是一种罕见的肿瘤,由恶性上皮和间充质成分组成。涎腺癌肉瘤本质上具有侵袭性,鉴于其双相组织学表现,它有可能被误诊为病情较轻的疾病。口腔内小涎腺癌肉瘤极为罕见,腭部是最常受累的部位。仅报告过两例起源于口底(FOM)的癌肉瘤病例。我们报告一例不愈合的口底溃疡病例,经手术病理确诊为小涎腺癌肉瘤,并阐述准确诊断的步骤及重要性。

相似文献

1
Minor Salivary Gland Carcinosarcoma of the Floor of the Mouth.口腔底部小唾液腺癌肉瘤
Cureus. 2023 Apr 6;15(4):e37206. doi: 10.7759/cureus.37206. eCollection 2023 Apr.
2
True malignant mixed tumor (carcinosarcoma) of palatal minor salivary gland origin.起源于腭部小涎腺的真性恶性混合瘤(癌肉瘤)。
Ann Dent. 1991 Summer;50(1):33-5.
3
[Extremely rapid progression of oral cavity carcinosarcoma].[口腔癌肉瘤的极速进展]
Rev Stomatol Chir Maxillofac Chir Orale. 2013 Dec;114(6):356-9. doi: 10.1016/j.revsto.2013.07.007. Epub 2013 Aug 22.
4
Patterns of Care and Outcomes of Carcinosarcoma of the Major Salivary Glands.大唾液腺癌肉瘤的治疗模式与预后
Otolaryngol Head Neck Surg. 2023 Apr;168(4):775-781. doi: 10.1177/01945998221120646. Epub 2023 Jan 29.
5
Initial report of a case of carcinosarcoma of the supraglottis.声门上区癌肉瘤1例的初步报告。
Ear Nose Throat J. 2000 May;79(5):384-7.
6
Primary Carcinosarcoma of the Parotid Gland Mimicking as Parotid Abscess With Deep Neck Infection.腮腺原发性癌肉瘤误诊为腮腺脓肿伴颈部深部感染
J Craniofac Surg. 2017 May;28(3):e210-e213. doi: 10.1097/SCS.0000000000003465.
7
Histomorphological investigation regarding to malignant transformation of pleomorphic adenoma (so-called malignant mixed tumor) of the salivary gland origin: special reference to carcinosarcoma.关于涎腺来源多形性腺瘤(所谓恶性混合瘤)恶变的组织形态学研究:特别提及癌肉瘤。
Kurume Med J. 2000;47(4):307-23. doi: 10.2739/kurumemedj.47.307.
8
Salivary gland carcinosarcoma: oligonucleotide array CGH reveals similar genomic profiles in epithelial and mesenchymal components.唾液腺癌肉瘤:寡核苷酸阵列 CGH 显示上皮和间充质成分具有相似的基因组图谱。
Oral Oncol. 2009 Mar;45(3):259-65. doi: 10.1016/j.oraloncology.2008.05.009. Epub 2008 Aug 6.
9
Intraoral carcinosarcoma on the floor of the mouth mimicking a benign lesion.口腔内口底的癌肉瘤,类似良性病变。
Int J Oral Maxillofac Surg. 2012 Aug;41(8):970-3. doi: 10.1016/j.ijom.2011.12.004. Epub 2012 Jan 21.
10
Carcinosarcoma of the parotid gland: cytological, clinicopathological and immunohistochemical study of a case.腮腺癌肉瘤:1例的细胞学、临床病理及免疫组织化学研究
Pathol Res Pract. 2000;196(7):511-7. doi: 10.1016/s0344-0338(00)80053-9.

本文引用的文献

1
Patterns of Care and Outcomes of Carcinosarcoma of the Major Salivary Glands.大唾液腺癌肉瘤的治疗模式与预后
Otolaryngol Head Neck Surg. 2023 Apr;168(4):775-781. doi: 10.1177/01945998221120646. Epub 2023 Jan 29.
2
Salivary Carcinosarcoma: An Extremely Rare and Highly Aggressive Malignancy.唾液腺癌肉瘤:一种极其罕见且极具侵袭性的恶性肿瘤。
Laryngoscope. 2020 May;130(5):E335-E339. doi: 10.1002/lary.28183. Epub 2019 Jul 10.
3
Carcinosarcoma de novo of the parotid gland: case report.腮腺新发癌肉瘤:病例报告。
Head Neck. 2013 May;35(5):E161-3. doi: 10.1002/hed.22900. Epub 2012 Feb 6.
4
Intraoral carcinosarcoma on the floor of the mouth mimicking a benign lesion.口腔内口底的癌肉瘤,类似良性病变。
Int J Oral Maxillofac Surg. 2012 Aug;41(8):970-3. doi: 10.1016/j.ijom.2011.12.004. Epub 2012 Jan 21.
5
Salivary gland carcinosarcoma: oligonucleotide array CGH reveals similar genomic profiles in epithelial and mesenchymal components.唾液腺癌肉瘤:寡核苷酸阵列 CGH 显示上皮和间充质成分具有相似的基因组图谱。
Oral Oncol. 2009 Mar;45(3):259-65. doi: 10.1016/j.oraloncology.2008.05.009. Epub 2008 Aug 6.
6
Malignant mixed tumors of the salivary gland: a study of loss of heterozygosity in tumor suppressor genes.涎腺恶性混合瘤:肿瘤抑制基因杂合性缺失的研究
Mod Pathol. 2006 Mar;19(3):350-5. doi: 10.1038/modpathol.3800533.
7
Malignant mixed tumors of the salivary glands: a review.涎腺恶性混合瘤:综述
Pathol Annu. 1993;28 Pt 1:279-328.
8
Carcinosarcoma of salivary glands with unusual stromal components. Report of two cases and review of the literature.伴有不寻常间质成分的涎腺癌肉瘤:两例报告并文献复习
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1995 Jun;79(6):738-46. doi: 10.1016/s1079-2104(05)80309-9.
9
Carcinomas ex pleomorphic adenoma and malignant mixed tumors. Histomorphologic indexes.多形性腺瘤恶变及恶性混合瘤。组织形态学指标。
Arch Otolaryngol. 1984 Mar;110(3):172-6. doi: 10.1001/archotol.1984.00800290036008.
10
Carcinosarcoma of accessory salivary gland. First report of a case.副唾液腺癌肉瘤。首例病例报告。
Oral Surg Oral Med Oral Pathol. 1967 May;23(5):651-9. doi: 10.1016/0030-4220(67)90348-9.