Orme I M, Roberts A R, Collins F M
Tubercle. 1986 Mar;67(1):41-6. doi: 10.1016/0041-3879(86)90030-9.
Subcutaneous BCG vaccination of mice several weeks after intravenous or subcutaneous infection with either M. avium or M. kansasii had no effect on the subsequent course of these nontuberculous mycobacterial infections. In some animals the growth of the BCG infection in the draining popliteal lymph nodes was reduced compared with the growth in controls, although these mice were as resistant as BCG-vaccinated controls to a subsequent airborne challenge infection with M. tuberculosis. Nonvaccinated previously infected mice also showed some degree of resistance to the airborne challenge infection; this resistance was more pronounced in mice infected with nontuberculous mycobacteria intravenously than in those infected subcutaneously.
在用鸟分枝杆菌或堪萨斯分枝杆菌静脉内或皮下感染小鼠数周后，对其进行皮下卡介苗接种，对这些非结核分枝杆菌感染的后续病程没有影响。在一些动物中，与对照组相比，引流的腘窝淋巴结中卡介苗感染的生长有所减少，尽管这些小鼠与接种卡介苗的对照组一样，对随后的结核分枝杆菌空气传播攻击感染具有抗性。先前感染但未接种疫苗的小鼠对空气传播攻击感染也表现出一定程度的抗性；这种抗性在静脉内感染非结核分枝杆菌的小鼠中比在皮下感染的小鼠中更明显。
