Rades Dirk, Al-Salool Ahmed, Yu Nathan Y, Soror Tamer
Department of Radiation Oncology, University of Lübeck, Lübeck, Germany.
Department of Radiation Oncology, Mayo Clinic, Phoenix, AZ, U.S.A.
Cancer Diagn Progn. 2023 May 3;3(3):320-326. doi: 10.21873/cdp.10218. eCollection 2023 May-Jun.
BACKGROUND/AIM: Patients with gynecologic cancers selected for external-beam radiotherapy or brachytherapy may experience emotional distress. We aimed to identify patients who may benefit from early psycho-oncological intervention.
We investigated 10 potential risk factors of emotional distress in a retrospective series of 122 patients planned for radiotherapy of gynecologic cancers. Factors included COVID-19 pandemic, number of physical problems, age, performance status, tumor site/stage, surgery, chemotherapy, brachytherapy, and history of another tumor. p-Values <0.005 indicated significance, and p-values <0.06 trends.
Frequencies of worry, fear, sadness, depression, nervousness, and loss of interest were 41%, 57%, 39%, 16%, 38%, and 20%, respectively. Significant associations with at least one of these symptoms were found for ≥5 physical problems and no upfront surgery. Trends were observed for chemoradiotherapy, history of another tumor, worse performance status, and younger age.
The prevalence of pre-radiotherapy emotional distress was remarkable in patients with gynecologic cancers. Patients with risk factors may benefit from immediate psycho-oncological assistance.
背景/目的：被选接受外照射放疗或近距离放疗的妇科癌症患者可能会经历情绪困扰。我们旨在确定可能从早期心理肿瘤学干预中获益的患者。
我们在一项针对122例计划接受妇科癌症放疗患者的回顾性研究中调查了10个情绪困扰的潜在风险因素。这些因素包括新冠疫情、身体问题数量、年龄、体能状态、肿瘤部位/分期、手术、化疗、近距离放疗以及既往有其他肿瘤病史。p值<0.005表示有显著意义，p值<0.06表示有趋势。
担忧、恐惧、悲伤、抑郁、紧张和兴趣丧失的发生率分别为41%、57%、39%、16%、38%和20%。发现≥5个身体问题且未进行前期手术与这些症状中的至少一种有显著关联。在放化疗、既往有其他肿瘤病史、体能状态较差和年龄较小方面观察到有趋势。
妇科癌症患者放疗前情绪困扰的发生率较高。有风险因素的患者可能从即时的心理肿瘤学援助中获益。
