Albert D M, Pruett R C, Craft J L
Am J Ophthalmol. 1986 Jun 15;101(6):665-72. doi: 10.1016/0002-9394(86)90766-x.
Ultrastructural studies of six vitreous biopsy specimens obtained during cataract surgery on patients with retinitis pigmentosa showed four types of cells. These were ocular pigment epithelium, uveal melanocytes, retinal astrocytes, and macrophage-like cells. The fibrous astrocytes displayed plump cell bodies, large nuclei, and numerous intracytoplasmic filaments. The pigment epithelial cells and uveal melanocytes were round to cuboidal and were heavily pigmented. Macrophage-like cells demonstrated round cell bodies, inclusions of glycogen, and long processes extending from the cell membrane. Also identified in the vitreous material were loose pigment granules. In contrast, vitreous from the control group showed occasional macrophages and loose pigment. These findings explained the clinical observation of material within the vitreous of patients with retinitis pigmentosa.
对6例患有色素性视网膜炎的患者在白内障手术期间获取的玻璃体活检标本进行的超微结构研究显示有4种细胞类型。这些细胞为眼色素上皮细胞、葡萄膜黑素细胞、视网膜星形胶质细胞和巨噬细胞样细胞。纤维性星形胶质细胞呈现饱满的细胞体、大细胞核以及众多胞质内细丝。色素上皮细胞和葡萄膜黑素细胞呈圆形至立方形，且色素沉着严重。巨噬细胞样细胞表现为圆形细胞体、糖原包涵体以及从细胞膜伸出的长突起。在玻璃体物质中还发现了松散的色素颗粒。相比之下，对照组的玻璃体中偶尔可见巨噬细胞和松散的色素。这些发现解释了色素性视网膜炎患者玻璃体内物质的临床观察结果。
