Department of Community Health & Preventive Medicne, Microbiology, Biochemistry and Immunology, and Clinical Research Center, Morehouse School of Medicine, Atlanta, GA 30310, USA.
Department of Epidemiology and Health Services Research, University of Florida, Gainesville, FL 32611, USA.
Int J Environ Res Public Health. 2023 May 8;20(9):5738. doi: 10.3390/ijerph20095738.
The National Research Mentoring Network (NRMN) Strategic Empowerment Tailored for Health Equity Investigators (SETH) study evaluates the value of adding Developmental Network to Coaching in the career advancement of diverse Early-Stage Investigators (ESIs). Focused NIH-formatted Mock Reviewing Sessions (MRS) prior to the submission of grants can significantly enhance the scientific merits of an ESI's grant application. We evaluated the most prevalent design, analysis-related factors, and the likelihood of grant submissions and awards associated with going through MRS, using descriptive statistics, Chi-square, and logistic regression methods. A total of 62 out of 234 applications went through the MRS. There were 69.4% that pursued R grants, 22.6% career development (K) awards, and 8.0% other grant mechanisms. Comparing applications that underwent MRS versus those that did not (N = 172), 67.7% vs. 38.4% were submitted for funding (i.e., unadjusted difference of 29.3%; OR = 4.8, 95% CI = (2.4, 9.8), -value < 0.0001). This indicates that, relative to those who did not undergo MRS, ESIs who did, were 4.8 times as likely to submit an application for funding. Also, ESIs in earlier cohorts (1-2) (a period that coincided with the pre COVID-19 era) as compared to those who were recruited at later cohorts (3-4) (i.e., during the peak of COVID-19 period) were 3.8 times as likely to submit grants (-value < 0.0001). The most prevalent issues that were identified included insufficient statistical design considerations and plans (75%), conceptual framework (28.3%), specific aims (11.7%), evidence of significance (3.3%), and innovation (3.3%). MRS potentially enhances grant submissions for extramural funding and offers constructive feedback allowing for modifications that enhance the scientific merits of research grants.
国家研究指导网络(NRMN)战略授权促进健康公平调查员(SETH)研究评估了在职业发展中为多元化早期阶段调查员(ESI)增加发展网络和指导的价值。在提交资助申请之前,进行重点关注 NIH 格式的模拟评审会议(MRS)可以显著提高 ESI 资助申请的科学价值。我们使用描述性统计、卡方检验和逻辑回归方法评估了最常见的设计、分析相关因素,以及与经历 MRS 相关的资助申请和奖励的可能性。在 234 项申请中,共有 62 项申请通过了 MRS。其中 69.4%是 R 类资助,22.6%是职业发展(K)奖,8.0%是其他资助机制。与未参加 MRS 的申请相比(N=172),67.7%的申请被提交以寻求资助,而未参加 MRS 的申请仅为 38.4%(未调整差异为 29.3%;OR=4.8,95%CI=(2.4,9.8),-值<0.0001)。这表明,与未参加 MRS 的 ESI 相比,参加 MRS 的 ESI 提交资助申请的可能性是未参加 MRS 的 ESI 的 4.8 倍。此外,与在较晚队列(3-4)(即在 COVID-19 高峰期)招募的 ESI 相比,在较早队列(1-2)(这一时期恰逢 COVID-19 之前)的 ESI 提交资助申请的可能性要高出 3.8 倍(-值<0.0001)。发现的最常见问题包括统计设计考虑和计划不足(75%)、概念框架(28.3%)、具体目标(11.7%)、显著性证据(3.3%)和创新性(3.3%)。MRS 有可能增加外部资助的资助申请,并提供建设性反馈,允许进行修改,从而提高研究资助的科学价值。