Institute and Department of Endocrinology and Metabolism, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Zhizaoju Road No.639, Huangpu, Shanghai 200011, China.
School of Public Health, Zhejiang University, Hangzhou, China.
Eur J Prev Cardiol. 2023 Sep 20;30(13):1361-1370. doi: 10.1093/eurjpc/zwad167.
Recent studies have demonstrated the associations of the consumption of different beverages with cardiometabolic diseases, whereas no studies have investigated such associations in heart failure (HF). Thus, this study aimed to explore the associations of the consumption of sugar-sweetened beverages (SSBs), artificially sweetened beverages (ASBs), and pure fruit/vegetable juices (PJs) with the risk of incident HF.
This prospective cohort study included 209 829 participants in the UK Biobank who completed at least one 24-h diet questionnaire and who were free of baseline HF. Cox proportional hazard models were used to estimate the hazard ratios (HRs) and 95% confidence intervals (CIs). During a median follow-up of 9.9 years, 4328 incident HF cases were recorded. Compared to corresponding non-consumers, individuals who consumed >2 L/week SSBs or ASBs had an increased risk of HF (HR: 1.22, 95% CI: 1.08-1.38 and HR: 1.30, 95% CI: 1.16-1.47, respectively) in the multivariate adjusted model. An inverse association was observed between the consumption of >0-1 L/week PJs and the risk of HF (HR, 0.90; 95% CI, 0.83-0.98). Additionally, a significant interaction was observed between PJ consumption and sleep duration on HF risk (P for interaction = 0.030).
Increased consumption of SSBs or ASBs may be an independent risk factor for HF, whereas moderate intake of PJs may have a protective effect on HF.
最近的研究表明，饮用不同的饮料与心脏代谢疾病有关，而没有研究调查心力衰竭（HF）与这些饮料的关联。因此，本研究旨在探讨饮用含糖饮料（SSBs）、人工甜味饮料（ASBs）和纯水果/蔬菜汁（PJs）与新发 HF 风险的关系。
这项前瞻性队列研究纳入了英国生物库中的 209829 名参与者，他们至少完成了一次 24 小时饮食问卷，且基线时无 HF。使用 Cox 比例风险模型估计风险比（HR）和 95%置信区间（CI）。在中位随访 9.9 年期间，记录到 4328 例新发 HF 病例。与相应的非饮用者相比，每周饮用>2L SSBs 或 ASBs 的个体发生 HF 的风险增加（HR：1.22，95%CI：1.08-1.38 和 HR：1.30，95%CI：1.16-1.47，分别），在多变量调整模型中。每周饮用>0-1L PJs 与 HF 风险呈负相关（HR，0.90；95%CI，0.83-0.98）。此外，PJ 消费与睡眠时长对 HF 风险的交互作用具有统计学意义（P 交互=0.030）。
增加 SSBs 或 ASBs 的摄入量可能是 HF 的独立危险因素，而适量摄入 PJs 可能对 HF 具有保护作用。
