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作为左心室辅助装置植入术后的晚期并发症,结肠动力线侵蚀。

Driveline erosion of the colon as a late complication of LVAD implantation.

作者信息

Yan Crystal Lihong, Bauerlein E Joseph, Thakkar Rivera Nina

机构信息

Division of Internal Medicine, University of Miami/Jackson Memorial Hospital, Miami, FL, USA.

Division of Cardiology, Miami Transplant Institute, University of Miami Health System, Miami, FL, USA.

出版信息

J Cardiol Cases. 2023 Feb 9;27(5):226-228. doi: 10.1016/j.jccase.2023.02.001. eCollection 2023 May.

DOI:10.1016/j.jccase.2023.02.001
PMID:37180220
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10173392/
Abstract

UNLABELLED

A 69-year-old man with ischemic cardiomyopathy underwent left ventricular assist device (LVAD) implantation as destination therapy. One month after LVAD placement, the patient reported abdominal pain with driveline site purulence. Serial wound and blood cultures were positive for various Gram-positive and Gram-negative organisms. Abdominal imaging revealed a possible intracolonic course of the driveline at the splenic flexure, but there were no imaging findings suggestive of bowel perforation. A colonoscopy did not identify a perforation. The patient was treated with antibiotics but continued to experience driveline infections over the next 9 months until frank stool started draining from the driveline exit site. Our case illustrates driveline erosion of the colon causing the insidious formation of an enterocutaneous fistula and highlights a rare late complication of LVAD therapy.

LEARNING OBJECTIVE

Colonic erosion by the driveline can cause enterocutaneous fistula formation over a period of months. A change from typical infectious organisms for driveline infection should prompt investigation of a gastrointestinal source. In cases where computed tomography of the abdomen does not show perforation and there is concern for an intracolonic course of the driveline, colonoscopy or laparoscopy may be diagnostic.

摘要

未标注

一名69岁的缺血性心肌病男性患者接受了左心室辅助装置(LVAD)植入作为终末期治疗。LVAD植入后一个月,患者报告腹痛且 driveline 部位有脓性分泌物。连续的伤口和血液培养对多种革兰氏阳性菌和革兰氏阴性菌呈阳性。腹部影像学检查显示 driveline 在脾曲处可能有结肠内走行,但没有影像学表现提示肠穿孔。结肠镜检查未发现穿孔。患者接受了抗生素治疗,但在接下来的9个月中仍持续出现 driveline 感染,直到粪便开始从 driveline 出口部位流出。我们的病例说明了结肠的 driveline 侵蚀导致肠皮肤瘘的隐匿形成,并突出了LVAD治疗罕见的晚期并发症。

学习目标

driveline 对结肠的侵蚀可在数月内导致肠皮肤瘘形成。从 driveline 感染的典型感染病原体发生变化应促使对胃肠道来源进行调查。在腹部计算机断层扫描未显示穿孔且担心 driveline 有结肠内走行的情况下,结肠镜检查或腹腔镜检查可能具有诊断价值。

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本文引用的文献

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J Cardiothorac Surg. 2020 Jul 28;15(1):193. doi: 10.1186/s13019-020-01240-w.
2
Role of imaging in diagnosis and management of left ventricular assist device complications.影像学在左心室辅助装置并发症诊断与管理中的作用
Int J Cardiovasc Imaging. 2019 Jul;35(7):1365-1377. doi: 10.1007/s10554-019-01562-4. Epub 2019 Mar 4.
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Abdominal wall perforation caused by left ventricular assist device driveline insertion: Potential lethal complication.左心室辅助装置驱动线插入导致的腹壁穿孔:潜在的致命并发症。
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Contributory Role of Fluorine 18-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in the Diagnosis and Clinical Management of Infections in Patients Supported With a Continuous-Flow Left Ventricular Assist Device.氟-18-氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描在连续血流左心室辅助装置支持的患者感染诊断及临床管理中的辅助作用
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Technique for minimizing and treating driveline infections.减少和治疗动力线感染的技术。
Ann Cardiothorac Surg. 2014 Nov;3(6):557-62. doi: 10.3978/j.issn.2225-319X.2014.09.08.
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Prospective, multicenter study of ventricular assist device infections.前瞻性、多中心心室辅助装置感染研究。
Circulation. 2013 Feb 12;127(6):691-702. doi: 10.1161/CIRCULATIONAHA.112.128132. Epub 2013 Jan 11.
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