Dubey Snigdha, Tiwari Gaurav, Singh Sneha, Goldberg Saveli, Pinsky Eugene
Department of Computer Science, Metropolitan College, Boston University, Boston, MA, United States.
Department of Radiation Oncology Mass General Hospital, Boston, MA, United States.
Front Artif Intell. 2023 Apr 25;6:1124182. doi: 10.3389/frai.2023.1124182. eCollection 2023.
We present a methodology for using machine learning for planning treatments. As a case study, we apply the proposed methodology to Breast Cancer. Most of the application of Machine Learning to breast cancer has been on diagnosis and early detection. By contrast, our paper focuses on applying Machine Learning to suggest treatment plans for patients with different disease severity. While the need for surgery and even its type is often obvious to a patient, the need for chemotherapy and radiation therapy is not as obvious to the patient. With this in mind, the following treatment plans were considered in this study: chemotherapy, radiation, chemotherapy with radiation, and none of these options (only surgery). We use real data from more than 10,000 patients over 6 years that includes detailed cancer information, treatment plans, and survival statistics. Using this data set, we construct Machine Learning classifiers to suggest treatment plans. Our emphasis in this effort is not only on suggesting the treatment plan but on explaining and defending a particular treatment choice to the patient.
我们提出了一种利用机器学习进行治疗规划的方法。作为一个案例研究,我们将所提出的方法应用于乳腺癌。机器学习在乳腺癌方面的大多数应用都集中在诊断和早期检测上。相比之下,我们的论文重点在于应用机器学习为不同疾病严重程度的患者推荐治疗方案。虽然手术需求甚至其类型对患者来说通常是显而易见的,但化疗和放疗需求对患者来说并不那么明显。考虑到这一点,本研究考虑了以下治疗方案:化疗、放疗、化疗联合放疗以及不采用这些方案(仅手术)。我们使用了6年多来超过10000名患者的真实数据,这些数据包括详细的癌症信息、治疗方案和生存统计数据。利用这个数据集,我们构建机器学习分类器来推荐治疗方案。我们在这项工作中的重点不仅在于推荐治疗方案,还在于向患者解释和论证特定的治疗选择。