Khalid Haval Mohammed
Department of Biology, Faculty of Science, University of Zakho, Zakho, Kurdistan Region, Iraq.
Infect Drug Resist. 2023 May 8;16:2805-2811. doi: 10.2147/IDR.S407263. eCollection 2023.
Brucellosis is a zoonotic disease that contributes to severe global health and economic issues. In this study, the Rose Bengal Test (RBT), a crucial diagnostic tool for brucellosis in Duhok city, was evaluated in order to offer updated epidemiological data on this disease.
A total of 339 patients suffered from fever and seeking medical attention in the private medical health center in Duhok city, Iraq, were enrolled after taking ethical approval from committee at Faculty of Sciences, University of Zakho and a verbal consent from each enrolled patient for using his/her blood and data. The blood specimens were tested for spp. Antibodies using the RBT and blood cultures, followed by spp. determination. A questionnaire form was designed to detect the associated risk factors.
Prevalence of brucellosis was 12.6% among participants with a probable diagnosis and 10.3% among those with a confirmed diagnosis (positive blood culture). Most of the positive cases were between the ages of 20 to 40 years. A highly significant (P < 0.0001) association was found between brucellosis with both consuming raw milk and having contact with cattle. The most common species identified were (57.1%) and (42.7%).
Brucellosis is a significant cause of fever in the current study and can be detected using the RBT. Human brucellosis can be reduced by minimizing the chances of contact with cattle and consuming boiled or pasteurized milk.
布鲁氏菌病是一种人畜共患病，会引发严重的全球健康和经济问题。在本研究中，对玫瑰红试验（RBT）这一杜胡克市布鲁氏菌病的关键诊断工具进行了评估，以便提供关于该疾病的最新流行病学数据。
在获得扎胡大学理学院委员会的伦理批准以及每位入选患者关于使用其血液和数据的口头同意后，纳入了伊拉克杜胡克市私立医疗健康中心共339名发烧并寻求医疗救治的患者。使用RBT和血培养对血液标本进行布鲁氏菌属抗体检测，随后进行布鲁氏菌属鉴定。设计了一份问卷以检测相关危险因素。
在可能诊断为布鲁氏菌病的参与者中患病率为12.6%，在确诊（血培养阳性）患者中为10.3%。大多数阳性病例年龄在20至40岁之间。发现布鲁氏菌病与饮用生牛奶和接触牛均存在高度显著关联（P < 0.0001）。鉴定出的最常见菌种是马尔他布鲁氏菌（57.1%）和流产布鲁氏菌（42.7%）。
在本研究中，布鲁氏菌病是发热的一个重要原因，可通过RBT检测出来。通过尽量减少与牛接触的机会以及饮用煮沸或巴氏消毒牛奶，可降低人类布鲁氏菌病的发病率。
