Carswell F, Oliver J, Silverman M
Clin Exp Immunol. 1979 Jan;35(1):141-6.
Forty-four patients with cystic fibrosis, sixty-seven parents, and thirty-nine controls were compared with regard to their immediate cutaneous hypersensitivity, total and specific serum IgE and serum IgG4 concentrations. The patients had increased prick test reactions and specific IgE to Aspergillus fumigatus. The development of reactions to A. fumigatus correlated with the severity of the disease. There were no other significant differences when serum total IgE, specific IgE and IgG4 concentrations or skin test reactivity were compared in the patients, parents and controls.
对44例囊性纤维化患者、67名家长及39名对照者的即刻皮肤超敏反应、血清总IgE和特异性IgE以及血清IgG4浓度进行了比较。患者对烟曲霉的点刺试验反应及特异性IgE增加。对烟曲霉反应的发生与疾病严重程度相关。在患者、家长和对照者中比较血清总IgE、特异性IgE和IgG4浓度或皮肤试验反应性时,未发现其他显著差异。