透明质酸钠（0.1%）对干眼症患者泪膜破裂时间（NIBUT）的影响。
Effect of sodium hyaluronate (0.1%) on break-up time (NIBUT) in patients with dry eyes.
作者信息
Mengher L S, Pandher K S, Bron A J, Davey C C
出版信息
Br J Ophthalmol. 1986 Jun;70(6):442-7. doi: 10.1136/bjo.70.6.442.
Abstract
We evaluated the effect of 0.1% sodium hyaluronate (unpreserved) in 10 patients with dry eyes. The precorneal tear film break-up time was assessed by the non-invasive technique, and the severity of symptoms was recorded before and after treatment on a 0 to +3 scale. It was found that the tear film stability was significantly increased (p less than 0.05) in eyes treated with sodium hyaluronate. The symptoms of grittiness and burning were also significantly alleviated in the treated eyes.
摘要
我们评估了0.1%的透明质酸钠（未添加防腐剂）对10例干眼症患者的疗效。采用非侵入性技术评估角膜前泪膜破裂时间，并在治疗前后以0至+3级记录症状的严重程度。结果发现，使用透明质酸钠治疗的眼睛，其泪膜稳定性显著提高（p小于0.05）。治疗后的眼睛中，磨砂感和烧灼感等症状也得到了显著缓解。
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本文引用的文献
1
Cellulose acetate impressions of the ocular surface. Dry eye states.眼表醋酸纤维素印模。干眼状态。
Arch Ophthalmol. 1983 Dec;101(12):1869-72. doi: 10.1001/archopht.1983.01040020871007.
2
The use of topical Healon tears in the management of refractory dry-eye syndrome.局部应用透明质酸钠滴眼液治疗难治性干眼综合征
Ann Ophthalmol. 1984 Sep;16(9):823-4.
3
Kinetics of lacrimal secretions in normal human subject.正常人类受试者泪液分泌的动力学
Curr Eye Res. 1984 Jul;3(7):897-910. doi: 10.3109/02713688409167207.
4
Recent advances in ocular surface chemistry.眼表化学的最新进展。
Am J Optom Arch Am Acad Optom. 1970 Sep;47(9):669-72. doi: 10.1097/00006324-197009000-00001.
5
Artificial tear solutions.人工泪液制剂
Int Ophthalmol Clin. 1973 Spring;13(1):221-9. doi: 10.1097/00004397-197301310-00016.
6
Management of the dry eye in Sjogren's syndrome.干燥综合征干眼的管理
Br J Ophthalmol. 1974 Sep;58(9):798-805. doi: 10.1136/bjo.58.9.798.
7
Diagnostic tests in the Sicca syndrome.干燥综合征的诊断测试。
Arch Ophthalmol. 1969 Jul;82(1):10-4. doi: 10.1001/archopht.1969.00990020012003.
8
Effect of fluorescein instillation on the pre-corneal tear film stability.荧光素滴注对角膜前泪膜稳定性的影响。
Curr Eye Res. 1985 Jan;4(1):9-12. doi: 10.3109/02713688508999961.
9
A non-invasive instrument for clinical assessment of the pre-corneal tear film stability.一种用于临床评估角膜前泪膜稳定性的非侵入性仪器。
Curr Eye Res. 1985 Jan;4(1):1-7. doi: 10.3109/02713688508999960.
10
Extraocular fluid dynamics: how best to apply topical ocular medication.眼外流体动力学：如何最佳应用局部眼用药物。
Trans Am Ophthalmol Soc. 1976;74:457-87.
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