Sami Hiba, Firoze Safiya, Khan Parvez A, Fatima Nazish, Khan Haris M
Department of Microbiology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India.
Iran J Microbiol. 2023 Apr;15(2):181-188. doi: 10.18502/ijm.v15i2.12466.
There are conflicting views regarding face mask guidelines amongst healthcare staff to prevent transmission of coronavirus disease 2019 (COVID-19), influenza and other respiratory viral infections (RVIs). We conducted a thorough meta-analysis to statistically compare mask use versus no mask use efficacy for RVIs in healthcare settings.
Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines were used for selecting researches published between 2003 and June 2022 from different databases, including Publisher Medline (PubMed), Web of Science, etc.; 6 studies qualified for inclusion. Data was pooled from in vivo randomized control, case-control and observational studies dealing with the relationship between face mask use and no use by patients or health personnel and RVI prevention in healthcare setups.
The fixed and random-effects model was carried out to determine pooled odds ratios (ORs) and their respective 95 percent confidence intervals (CIs). The results revealed that wearing a face mask significantly reduced the risk of contracting a respiratory viral illness in hospital settings, with pooled OR (95% CI) of 0.11 (0.04 to 0.33) (probability value (P) <0.08).
Masks largely succeeded in stopping respiratory virus transmission, as evidenced by the meta-analysis of 6 studies (a total of 927 individuals).
在医护人员中，关于预防2019冠状病毒病（COVID - 19）、流感及其他呼吸道病毒感染（RVI）的口罩使用指南存在相互矛盾的观点。我们进行了一项全面的荟萃分析，以统计学方法比较在医疗环境中使用口罩与不使用口罩预防RVI的效果。
采用系统评价和荟萃分析的首选报告项目（PRISMA）指南，从不同数据库中筛选2003年至2022年6月发表的研究，包括医学期刊数据库（PubMed）、科学网等；6项研究符合纳入标准。数据汇集自关于患者或医护人员使用口罩与不使用口罩以及医疗环境中预防RVI之间关系的体内随机对照、病例对照和观察性研究。
采用固定效应模型和随机效应模型确定合并比值比（OR）及其各自的95%置信区间（CI）。结果显示，在医院环境中佩戴口罩显著降低了感染呼吸道病毒疾病的风险，合并OR（95%CI）为0.11（0.04至0.33）（概率值（P）<0.08）。
对6项研究（共927人）的荟萃分析表明，口罩在很大程度上成功阻止了呼吸道病毒的传播。
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