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金属氧化物和硫属化物作为抗菌剂的最新进展。

Recent development of metal oxides and chalcogenides as antimicrobial agents.

机构信息

Chemical Sciences, Faculty of Science, Universiti Brunei Darussalam, Jalan Tungku Link, Gadong, BE, 1410, Brunei Darussalam.

出版信息

Bioprocess Biosyst Eng. 2023 Sep;46(9):1231-1249. doi: 10.1007/s00449-023-02878-1. Epub 2023 May 18.

Abstract

Pathogenic microbes are a major concern in hospitals and other healthcare facilities because they affect the proper performance of medical devices, surgical devices, etc. Due to the antimicrobial resistance or multidrug resistance, combatting these microbial infections has grown to be a significant research area in science and medicine as well as a critical health concern. Antibiotic resistance is where microbes acquire and innately exhibit resistance to antimicrobial agents. Therefore, the development of materials with promising antimicrobial strategy is a necessity. Amongst other available antimicrobial agents, metal oxide and chalcogenide-based materials have shown to be promising antimicrobial agents due to their inherent antimicrobial activity as well as their ability to kill and inhibit the growth of microbes effectively. Moreover, other features including the superior efficacy, low toxicity, tunable structure, and band gap energy has makes metal oxides (i.e. TiO, ZnO, SnO and CeO in particular) and chalcogenides (AgS, MoS, and CuS) promising candidates for antimicrobial applications as illustrated by examples discussed in this review.

摘要

致病微生物是医院和其他医疗保健设施的主要关注点,因为它们会影响医疗器械、手术器械等的正常运行。由于抗菌药物耐药性或多药耐药性,对抗这些微生物感染已成为科学和医学领域的一个重要研究领域,也是一个关键的健康关注点。抗生素耐药性是指微生物获得并天生对抗菌药物具有耐药性。因此,开发具有有前途的抗菌策略的材料是必要的。在其他可用的抗菌剂中,基于金属氧化物和硫族化物的材料由于其固有抗菌活性以及有效杀死和抑制微生物生长的能力,已被证明是有前途的抗菌剂。此外,其他特性,包括卓越的功效、低毒性、可调结构和带隙能,使得金属氧化物(例如 TiO、ZnO、SnO 和 CeO 特别)和硫族化物(AgS、MoS 和 CuS)成为抗菌应用的有前途的候选材料,正如本综述中讨论的例子所示。

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