Department of Medical Genetics, Faculty of Medicine, Near East University, 99138, Nicosia, Cyprus.
Department of Medical Genetics, Faculty of Medicine, Near East University, 99138, Nicosia, Cyprus.
Clin Nutr ESPEN. 2023 Jun;55:1-9. doi: 10.1016/j.clnesp.2023.02.017. Epub 2023 Feb 21.
The most well-grounded dietary pattern involved in nutrigenenic studies investigating non -communicable diseases is the Mediterranean diet. This dietary regime is inspired by the nutritional habits of people residing near Mediterranean Sea. The fundamental elements of this diet can vary based on ethnicity, culture, economic status and religious properties and are associated with lowercases of all-cause mortality rates. Mediterranean diet is most studied dietary pattern at the level of evidence-based medicine. Nutritional based studies are dependent on combined data analysis from the multi-omics technique which delineates systematic alternations taking place fallowing exposure to a stimulant. Comprehending the physiological mechanisms of plant metabolites in cellular processes, in combination of Nutri-genetic and nutrigenomics association with multi omics approaches is a necessary step for developing personalized nutrition regime for a stronger management, treatment and prevention of chronic diseases. The advanced lifestyle is marked by abundant access to food and an accelerating trend of physical inactivity, the latter of which contribute to a variety of health problems. In light of the importance of excellent food habits in the prevention of chronic diseases, health policy should promote the adoption of healthy diets that sustain traditional dietary patterns in the face of commercial pressures.
在研究非传染性疾病的营养基因学研究中，最有充分依据的饮食模式是地中海饮食。这种饮食模式的灵感来自于居住在地中海附近的人们的营养习惯。这种饮食的基本要素因种族、文化、经济地位和宗教性质而异，与全因死亡率的降低有关。地中海饮食是循证医学水平上研究最多的饮食模式。基于营养的研究依赖于多组学技术的综合数据分析，该技术描绘了在接触刺激物后发生的系统变化。理解植物代谢物在细胞过程中的生理机制，结合营养遗传学和营养基因组学与多组学方法的关联，是为慢性病的更强管理、治疗和预防制定个性化营养方案的必要步骤。先进的生活方式以丰富的食物供应和加速的体力活动趋势为标志，后者导致了各种健康问题。鉴于良好的饮食习惯在预防慢性病方面的重要性，卫生政策应促进采取健康饮食，以应对商业压力，维持传统的饮食模式。
