Department for Experimental Toxicology and Pharmacology, National Poison Control Centre, Military Medical Academy, Crnotravska 17, 11000 Belgrade, Serbia; Medical Faculty of the Military Medical Academy, University of Defence, Crnotravska 17, 11000 Belgrade, Serbia; Department of Chemistry, Faculty of Science, University of Hradec Kralove, Rokitanského 62, 500 03 Hradec Králové, Czech Republic.
Medical Faculty of the Military Medical Academy, University of Defence, Crnotravska 17, 11000 Belgrade, Serbia; Department of Analytical Chemistry, Faculty of Chemistry, University of Belgrade, 11158 Belgrade, Serbia.
Toxicology. 2023 Jun 15;492:153549. doi: 10.1016/j.tox.2023.153549. Epub 2023 May 18.
Serious health risks associated with the consumption of food products contaminated with aflatoxins (AFs) are worldwide recognized and depend predominantly on consumed AF concentration by diet. A low concentration of aflatoxins in cereals and related food commodities is unavoidable, especially in subtropic and tropic regions. Accordingly, risk assessment guidelines established by regulatory bodies in different countries help in the prevention of aflatoxin intoxication and the protection of public health. By assessing the maximal levels of aflatoxins in food products which are a potential risk to human health, it's possible to establish appropriate risk management strategies. Regarding, a few factors are crucial for making a rational risk management decision, such as toxicological profile, adequate information concerning the exposure duration, availability of routine and some novel analytical techniques, socioeconomic factors, food intake patterns, and maximal allowed levels of each aflatoxin in different food products which may be varied between countries.
与食用受黄曲霉毒素（AFs）污染的食品相关的严重健康风险是全球性的，并主要取决于饮食中摄入的 AF 浓度。谷物和相关食品中低浓度的黄曲霉毒素是不可避免的，特别是在亚热带和热带地区。因此，不同国家的监管机构制定的风险评估指南有助于预防黄曲霉毒素中毒和保护公众健康。通过评估对人类健康有潜在风险的食品中黄曲霉毒素的最大水平，可以制定适当的风险管理策略。关于这一点，一些因素对于做出合理的风险管理决策至关重要，例如毒理学特征、关于暴露时间的充分信息、常规和一些新型分析技术的可用性、社会经济因素、食物摄入模式，以及不同国家可能不同的每种食品中允许的最大黄曲霉毒素水平。
