Hegde Sajan, Badikillaya Vigneshwara, Kanade Umesh, Akbari Keyur, Achar Sharan, Reddy Harith
Department of Orthopaedics & Spine Surgery, Apollo Hospitals, Chennai, India.
Asian Spine J. 2023 Jun;17(3):529-537. doi: 10.31616/asj.2022.0267. Epub 2023 May 22.
Retrospective cohort study.
This study aimed to evaluate the clinical and radiological outcomes of nonfusion anterior scoliosis correction (NFASC) in patients with idiopathic scoliosis and comprehensively analyze its principles.
NFASC is a novel revolutionary motion-preserving surgery for idiopathic scoliosis. However, clinical data related to this procedure remain scarce, with no conclusive guidelines regarding case indications, proper technique, and possible complications.
This study included patients with adolescent idiopathic scoliosis (AIS) who were treated with NFASC for a structural major curve (Cobb angle, 40°-80°) with more than 50% flexibility on dynamic X-rays. The mean follow-up was 26±12.2 months (range, 12- 60 months). Clinical and radiological data such as skeletal maturity, curve type, Cobb angle, surgery details, and Scoliosis Research Society-22 revised (SRS-22r) questionnaire were collected. Statistically significant trends were examined by post hoc analysis following repeated measures analysis of variance test.
A total of 75 patients (70 females, five males) were included, with a mean age of 14.96±2.69 years. The mean Risser and Sanders scores were 4.22±0.7 and 7.15±0.74, respectively. The mean main thoracic Cobb angles at the first and second follow-up (17.2°±5.36° and 16.92°±5.06°, respectively) were significantly lower than the preoperative Cobb angles (52.11°±7.74°) (p <0.05). Similarly, the mean thoracolumbar/lumbar Cobb angle significantly improved from the preoperative period (51.45°±11.26°) to the first follow-up (13.48°±5.11°) and last follow-up (14.24°±4.85°) (p <0.05). The mean preoperative and postoperative SRS-22r scores were 78.0±3.2 and 92.5±3.1, respectively (p <0.05). None of the patients had any complications until the most recent follow-up.
NFASC offers promising curve correction and curve progression stabilization in patients with AIS, with a low risk for complications and preservation of spinal mobility and sagittal parameters. Thus, it proves to be a favorable alternative to fusion modality.
回顾性队列研究。
本研究旨在评估特发性脊柱侧凸患者非融合前路脊柱侧凸矫正术(NFASC)的临床和影像学结果,并全面分析其原理。
NFASC是一种针对特发性脊柱侧凸的新型革命性保留运动手术。然而,与该手术相关的临床数据仍然稀缺,在病例适应症、适当技术和可能的并发症方面没有确凿的指南。
本研究纳入了接受NFASC治疗结构性主弯(Cobb角40° - 80°)且动态X线显示柔韧性超过50%的青少年特发性脊柱侧凸(AIS)患者。平均随访时间为26±12.2个月(范围12 - 60个月)。收集了骨骼成熟度、侧弯类型、Cobb角、手术细节以及脊柱侧凸研究学会-22修订版(SRS-22r)问卷等临床和影像学数据。在重复测量方差分析测试后,通过事后分析检查具有统计学意义的趋势。
共纳入75例患者(70例女性,5例男性),平均年龄为14.96±2.69岁。Risser和Sanders平均评分分别为4.22±0.7和7.15±0.74。首次和第二次随访时的平均主胸弯Cobb角(分别为17.2°±5.36°和16.92°±5.06°)显著低于术前Cobb角(52.11°±7.74°)(p<0.05)。同样,胸腰段/腰段Cobb角从术前(51.45°±11.26°)到首次随访(13.48°±5.11°)和末次随访(14.24°±4.85°)时显著改善(p<0.05)。术前和术后SRS-22r平均评分分别为78.0±3.2和92.5±3.1(p<0.05)。直到最近一次随访,没有患者出现任何并发症。
NFASC在AIS患者中提供了有前景的侧弯矫正和侧弯进展稳定效果,并发症风险低,保留了脊柱活动度和矢状面参数。因此,它被证明是融合术式的一个有利替代方案。