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可能由新型冠状病毒肺炎心肌炎导致的心源性休克——病例报告

Cardiogenic shock due to probable SARS-CoV-2 myocarditis-a case report.

作者信息

Klasen Martiene, Smit Marije, Renes Maurits, Damman Kevin, Droogh Joep M

机构信息

Department of Critical Care, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9700 RB, Groningen, The Netherlands.

Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

出版信息

Eur Heart J Case Rep. 2023 May 3;7(5):ytad232. doi: 10.1093/ehjcr/ytad232. eCollection 2023 May.

Abstract

BACKGROUND

Since the start of the COVID-19 pandemic, many case reports have been presented describing different cardiac symptoms due to the SARS-CoV-2 infection. However, severe cardiac failure due to COVID-19 seems to be rare.

CASE SUMMARY

A 30-year-old woman presented with COVID-19 and cardiogenic shock due to a lymphocytic myocarditis. Since she deteriorated under treatment with inotropes, she was referred to our centre, and veno-arterial extracorporeal life support was started. Subsequently, the aortic valve only opened sporadically, and spontaneous contrast appeared in the left ventricle (LV), pointing towards difficulties with unloading LV. Therefore, an Impella for venting the LV was implanted. After 6 days of mechanical circulatory support, her heart function recovered. All support could be weaned, and 2 months later, she had made a full recovery.

DISCUSSION

We presented a patient with severe cardiogenic shock due to an acute virus-negative lymphocytic myocarditis associated with a SARS-CoV-2 infection. Since the precise aetiology of SARS-CoV-2-related myocarditis remains to be elucidated and no virus could be detected in the heart, a causal relationship remains speculative.

摘要

背景

自新冠疫情开始以来,已有许多病例报告描述了由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染引起的不同心脏症状。然而,由新冠病毒疾病(COVID-19)导致的严重心力衰竭似乎较为罕见。

病例摘要

一名30岁女性因淋巴细胞性心肌炎出现新冠病毒疾病(COVID-19)并伴有心源性休克。由于她在使用强心剂治疗过程中病情恶化,被转诊至我们中心,并开始进行静脉-动脉体外膜肺氧合支持治疗。随后,主动脉瓣仅偶尔开放,左心室内出现自发显影,提示左心室卸载困难。因此,植入了用于左心室排气的Impella装置。经过6天的机械循环支持,她的心脏功能恢复。所有支持措施均得以撤机,2个月后,她完全康复。

讨论

我们报告了一名因与SARS-CoV-2感染相关的急性病毒阴性淋巴细胞性心肌炎而出现严重心源性休克的患者。由于SARS-CoV-2相关心肌炎的确切病因仍有待阐明,且在心脏中未检测到病毒,因此因果关系仍具有推测性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41a5/10198703/f135dc2d3192/ytad232f1.jpg

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