Park Je-Young, Lee Ji Su, Lee Soo Ran, Lee Dong Hun
Apkoo-Jung Oracle Dermatology Center, Seoul, Republic of Korea.
Department of Dermatology, Seoul National University Hospital, Seoul, Republic of Korea.
Clin Cosmet Investig Dermatol. 2023 May 15;16:1249-1255. doi: 10.2147/CCID.S402001. eCollection 2023.
Despite the increasing need for the improvement of enlarged facial pores, the treatment remains challenging. A few previous studies have reported the effects of micro-focused ultrasound with visualization (MFU-V) or intradermal incobotulinumtoxin-A (INCO) on enlarged facial pores.
To evaluate the efficacy and safety of combined treatment with superficial MFU-V and intradermal INCO for enlarged facial pores.
This single-center retrospective study included 20 patients treated with MFU-V and intradermal INCO to improve enlarged facial pores. Outcomes were evaluated 1, 4, 12, and 24 weeks after a single session of the combined procedure. Pore count and density were objectively quantitated using a three-dimensional scanner, and improvement was assessed using the physician and patient Global Aesthetic Improvement Scale (GAIS).
The mean pore count and density decreased after one week and decreased by up to 62% until 24 weeks. After one week, almost all patients (100% in physician GAIS and 95% in patient GAIS) showed improvement with a grade 3 (much improved) or higher. All adverse events were transient.
Combined treatment with MFU-V and intradermal INCO could be effective and safe for reducing enlarged facial pores; the improvements can be sustained for up to 24 weeks.
尽管改善面部毛孔粗大的需求日益增加，但治疗仍具有挑战性。先前的一些研究报告了可视化微聚焦超声（MFU-V）或皮内注射肉毒杆菌毒素A（INCO）对面部毛孔粗大的影响。
评估浅表MFU-V联合皮内注射INCO治疗面部毛孔粗大的疗效和安全性。
这项单中心回顾性研究纳入了20例接受MFU-V和皮内注射INCO治疗以改善面部毛孔粗大的患者。在单次联合治疗后的1、4、12和24周对结果进行评估。使用三维扫描仪客观定量毛孔数量和密度，并使用医生和患者的整体美学改善量表（GAIS）评估改善情况。
平均毛孔数量和密度在1周后下降，到24周时下降高达62%。1周后，几乎所有患者（医生GAIS评分为100%，患者GAIS评分为95%）显示改善程度达到3级（明显改善）或更高。所有不良事件均为短暂性。
MFU-V联合皮内注射INCO治疗面部毛孔粗大可能有效且安全；改善效果可持续长达24周。
