UMRi CNRS LIENSs, Université de La Rochelle, Littoral Environnement et Sociétés, 2 rue Olympe de Gouges, La Rochelle 17 000, France.
UMRi CNRS LIENSs, Université de La Rochelle, Littoral Environnement et Sociétés, 2 rue Olympe de Gouges, La Rochelle 17 000, France; ANSES, Laboratory for Food Safety, F-94701 Maisons-Alfort, France.
Mar Pollut Bull. 2023 Jul;192:114988. doi: 10.1016/j.marpolbul.2023.114988. Epub 2023 May 20.
Biomarkers involved in detoxification process (GST), oxidative stress (SOD and MDA), immune response (Laccase) and neurotoxic disorders (AChE) were analysed in Pacific oysters and blue mussels collected from 4 locations within the Pertuis sea (France). Seasonal variations of total pesticide mean concentrations were found in seawater with metolachlor being the main pesticide measured (up to 32 ng/L). The majority of pesticide concentrations in sediment were below the LOD. Seasonal contamination differences were evidenced for chlortoluron, especially in mussels where concentrations reached 16 ng/g (wet weight) during the winter, in the Charente estuary, but no relationships with any of the biomarkers selected arisen. Actually, low concentrations of alpha-, beta-BHC and alachlor were correlated to GST activity, and low levels of hexachlorobenzene were linked to the AChE activity and MDA content in oysters. In mussels, low concentrations of methylparathion, parathion and beta-BHC were correlated to laccase.
从法国 Pertuis 海域的 4 个地点采集的太平洋牡蛎和贻贝中，分析了参与解毒过程（GST）、氧化应激（SOD 和 MDA）、免疫反应（漆酶）和神经毒性紊乱（AChE）的生物标志物。海水中发现了总农药平均浓度的季节性变化，其中甲草胺是测量的主要农药（高达 32ng/L）。沉积物中的大多数农药浓度低于检测限。在冬季，尤其是在夏朗德河口的贻贝中，氯氨嘧啶的浓度达到 16ng/g（湿重），这表明季节性污染存在差异，但与所选的任何生物标志物都没有关系。实际上，α-、β-六氯环己烷和甲草胺的低浓度与 GST 活性相关，六氯苯的低水平与牡蛎中的 AChE 活性和 MDA 含量相关。在贻贝中，甲基对硫磷、对硫磷和β-六氯环己烷的低浓度与漆酶相关。
