Valiulla Mohamed Umer E, Halli Rajshekhar, Khandelwal Saurabh, Mittal Ananya, Singh Akanksha, Bhindora Kajal
Oral and Maxillofacial Surgery, Bharati Vidyapeeth Dental College and Hospital, Pune, IND.
Cureus. 2023 Apr 21;15(4):e37934. doi: 10.7759/cureus.37934. eCollection 2023 Apr.
Aims and objectives This study was carried out to evaluate the efficacy of 8.4% sodium bicarbonate-buffered local anesthetic solution and conventional local anesthetic in patients requiring bilateral maxillary orthodontic extractions in terms of pain on injection, onset of action, and duration of action. Methods 102 patients requiring bilateral maxillary orthodontic extractions were included in the study. Buffered local anesthetic was administered on one side while conventional local anesthesia (LA) was administered on the other side. Pain on injection was measured using a visual analogue scale, while onset of action was measured by probing the buccal mucosa after 30 seconds of administration and duration of action was measured by the time after which the patient experienced pain or took a rescue analgesic. The data was statistically analyzed to determine the significance. Results The pain during injection was found to be lesser at sites where buffered local anesthetic was administered (mean visual analogue scale (VAS) score = 2.4) as compared to conventional local anesthetic (mean VAS score = 3.9). The onset of action was faster with buffered local anesthetic (mean value = 62.3 seconds) as compared to conventional local anesthetic (mean value = 157.16 seconds). Lastly, the duration of action was found to be longer for buffered local anesthetic group (mean value = 225.65 minutes) as compared to conventional local anesthetic (mean value = 187 minutes). Conclusion 8.4% sodium bicarbonate-buffered local anesthetic was found to be more efficient than conventional local anesthetic in terms of reduction in pain on injection as well as faster onset and longer duration of action.
目的和目标 本研究旨在评估8.4%碳酸氢钠缓冲局部麻醉溶液和传统局部麻醉剂在需要双侧上颌正畸拔牙患者中的疗效，比较其注射时的疼痛、起效时间和作用持续时间。方法 102例需要双侧上颌正畸拔牙的患者纳入本研究。一侧给予缓冲局部麻醉剂，另一侧给予传统局部麻醉（LA）。使用视觉模拟量表测量注射时的疼痛，给药30秒后通过探查颊黏膜测量起效时间，通过患者出现疼痛或使用解救镇痛药的时间测量作用持续时间。对数据进行统计分析以确定其显著性。结果 发现与传统局部麻醉剂（平均视觉模拟量表（VAS）评分=3.9）相比，给予缓冲局部麻醉剂的部位注射时疼痛较轻（平均VAS评分=2.4）。与传统局部麻醉剂（平均值=157.16秒）相比，缓冲局部麻醉剂起效更快（平均值=62.3秒）。最后，发现缓冲局部麻醉剂组的作用持续时间更长（平均值=225.65分钟），而传统局部麻醉剂组为（平均值=187分钟）。结论 发现8.4%碳酸氢钠缓冲局部麻醉剂在减轻注射疼痛、更快起效和更长作用持续时间方面比传统局部麻醉剂更有效。
