Gorrela Harsha, Srujana Tangella, Arthi Sirivore
Department of Oral and Maxillofacial Surgery, MNR Dental College and Hospital, Sangareddy, Telangana, India.
Ann Maxillofac Surg. 2024 Jan-Jun;14(1):15-20. doi: 10.4103/ams.ams_168_21. Epub 2024 Jul 19.
Commercially available local anaesthetics are acidic solutions associated with the vasopressor sting on injection, relatively slower onset of action and pain during palatal injections. The above drawbacks can be addressed by anaesthetic buffering. This prospective study was aimed at comparing the efficacy of buffered and non-buffered local anaesthesia in the extraction of grossly decayed maxillary molar teeth in relation to pain on local infiltration, onset and duration of action of local anaesthesia.
This is a prospective randomised controlled trial done on 100 patients who required bilateral extraction of maxillary molar teeth. In the study group, patients were given buffered local anaesthesia (which was prepared by mixing 2% lignocaine with 1:80,000 adrenaline and 8.4% sodium bicarbonate) before extraction. In the control group, non-buffered local anaesthesia (2% lignocaine with 1:80,000 adrenaline) was given before extraction.
Statistical data confirmed that buffering reduces pain on infiltration, decreases the onset and increases the duration of action of the local anaesthesia compared to non-buffered local anaesthesia. All the parameters measured were statistically significant ( = 0.001).
The study concludes that buffered local anaesthesia was more beneficial than non-buffered local anaesthesia in reducing pain on injection, providing a quicker onset of local anaesthesia and increasing the duration of action of the local anaesthesia. Buffering is a safe, easy and efficient process and should be routinely followed to provide a better experience to the patients.
市售局部麻醉剂为酸性溶液，注射时伴有血管收缩剂刺痛感，起效相对较慢且腭部注射时会引起疼痛。上述缺点可通过麻醉缓冲来解决。本前瞻性研究旨在比较缓冲型和非缓冲型局部麻醉在拔除严重龋坏的上颌磨牙时，局部浸润疼痛、局部麻醉起效时间和作用持续时间方面的效果。
这是一项对100例需要双侧拔除上颌磨牙的患者进行的前瞻性随机对照试验。研究组患者在拔牙前给予缓冲型局部麻醉（由2%利多卡因与1:80,000肾上腺素和8.4%碳酸氢钠混合配制而成）。对照组患者在拔牙前给予非缓冲型局部麻醉（2%利多卡因与1:80,000肾上腺素）。
统计数据证实，与非缓冲型局部麻醉相比，缓冲可减轻浸润时的疼痛，缩短起效时间并延长局部麻醉的作用持续时间。所有测量参数均具有统计学意义（P = 0.001）。
该研究得出结论，在减轻注射疼痛、使局部麻醉起效更快以及延长局部麻醉作用持续时间方面，缓冲型局部麻醉比非缓冲型局部麻醉更具优势。缓冲是一个安全、简便且有效的过程，应常规采用以给患者提供更好的体验。
