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埃塞俄比亚西南部布诺贝德莱和伊卢巴博尔地区糖尿病患者长寿的预测因素

Predictors for the Longevity of People with Diabetes in Buno Bedele and Illubabor Zones, South-west Ethiopia.

作者信息

Tadege Melaku, Misganaw Azmeraw, Truneh Zemenay, Tegegne Awoke Seyoum

机构信息

Department of Statistics, Injibara University, Injibara, Amhara, Ethiopia.

Department of Statistics, Mettu University, Mettu, Oromia, Ethiopia.

出版信息

Diabetes Metab Syndr Obes. 2023 May 18;16:1449-1457. doi: 10.2147/DMSO.S403556. eCollection 2023.

Abstract

INTRODUCTION

Currently, diabetes is a global health problem and it affects many people, especially in the developing continents. As patients' living conditions improve and the science of medicine advances, the longevity of such patients has increased greatly. Therefore, the purpose of this study was to identify predictors for the association of the longevity of people with diabetes in Buno Bedele and Illubabor Zones, South-west Ethiopia.

METHODS

The study applied a retrospective cohort study design approach. In particular, long rank tests for longevity experience and Cox semi-parametric regression were implemented to compare and investigate the predictors associated with the longevity of patients with diabetes.

RESULTS

Among all the patients who participated in this study, 56.9% were females and the rest were males. From the Cox regression result, age (AHR = 1.0550, 95% CI: (1.0250, 1.0860), p-value = 0.001), female patients (AHR = 0.2200, 95% CI: (0.0390, 0.5290)), rural patients (AHR = 0.2200, 95% CI: (0.1000, 0.4890), p-value = 0.001), the existence of fasting blood glucose complication (AHR = 1.2040, 95% CI: (1.0930, 1.4460), p-value = 0.001), the existence of blood pressure (AHR = 1.2480, 95% CI: (1.1390, 1.5999), p-value = 0.0180), treatment type, Sulfonylureas (AHR = 4.9970, 95% CI: (1.4140, 17.6550), p-value = 0.0120), treatment type, Sulfonylurea and Metformin (AHR = 5.7200, 95% CI: (1.7780, 18.3990), p-value = 0.0030) were significantly affected the longevity of people with diabetes.

CONCLUSION

The findings of the current study showed that the patient's age, sex of patients, residence area, the existence of complications, existence of pressure, and treatment type were major risk factors related to the longevity of people with diabetes. Hence, health-related education should be given to patients who come to take treatment to have better longevity for people with diabetes. More attention should be given to aged patients, male and urban patients, patients under complication treatment, and patients under treatment with single-treatment medication.

摘要

引言

目前,糖尿病是一个全球性的健康问题,影响着许多人,尤其是在发展中大陆。随着患者生活条件的改善和医学科学的进步,此类患者的寿命大幅延长。因此,本研究的目的是确定埃塞俄比亚西南部布诺贝德莱和伊卢巴博尔地区糖尿病患者寿命相关的预测因素。

方法

本研究采用回顾性队列研究设计方法。具体而言,实施了寿命经验的长秩检验和Cox半参数回归,以比较和研究与糖尿病患者寿命相关的预测因素。

结果

在所有参与本研究的患者中,56.9%为女性,其余为男性。从Cox回归结果来看,年龄(风险比=1.0550,95%置信区间:(1.0250, 1.0860),p值=0.001)、女性患者(风险比=0.2200,95%置信区间:(0.0390, 0.5290))、农村患者(风险比=0.2200,95%置信区间:(0.1000, 0.4890),p值=0.001)、空腹血糖并发症的存在(风险比=1.2040,95%置信区间:(1.0930, 1.4460),p值=0.001)、血压的存在(风险比=1.2480,95%置信区间:(1.1390, 1.5999),p值=0.0180)、治疗类型,磺脲类药物(风险比=4.9970,95%置信区间:(1.4140, 17.6550),p值=0.0120)、治疗类型,磺脲类药物和二甲双胍(风险比=5.7200,95%置信区间:(1.7780, 18.3990),p值=0.0030)对糖尿病患者的寿命有显著影响。

结论

本研究结果表明,患者的年龄、患者性别、居住地区、并发症的存在、压力的存在以及治疗类型是与糖尿病患者寿命相关的主要风险因素。因此,应向前来接受治疗的患者提供与健康相关的教育,以使糖尿病患者有更好的寿命。应更多关注老年患者、男性和城市患者、接受并发症治疗的患者以及接受单一治疗药物治疗的患者。

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