Gür Volkan, Yapici Furkan, Küçük Uğur, Subaşi İzzet Özay, Gökgöz Mehmet Burak, Karaköse Reşit, Koçkara Nizamettin
Department of Orthopedics and Traumatology, Faculty of Medicine, Erzincan University, 24180 Erzincan, Turkey.
Department of Cardiology, Faculty of Medicine, 18 Mart University, 17020 Çanakkale, Turkey.
J Clin Med. 2023 May 21;12(10):3583. doi: 10.3390/jcm12103583.
This study aimed to examine the ventricular repolarization (VR) disturbances of patients operated on for acute spontaneous Achilles tendon ruptures (ATRs), by comparing them with a healthy individual control group.
Between June 2014 and July 2020, a total of 29 patients (28 males, 1 female; mean age: 40 ± 9.78 years; range, 21-66 years) who presented to the emergency department within the first three weeks of injury, and were diagnosed with acute spontaneous ATRs and treated with an open Krackow suture technique, were retrospectively analyzed. Fifty-two healthy individuals (47 males, 5 females; mean age: 39 ± 11.45 years; range, 21-66 years) were recruited as a control group from the cardiology outpatient clinic. Clinical data (demographic features and laboratory parameters (serum glucose, creatinine, hemoglobin, white blood cell count, and lipid profile)) and electrocardiograms (ECGs) were collected from medical records. ECGs were evaluated for heart rate and VR parameters of QRS width, QTc interval, cQTd interval, Tp-e interval, and Tp-e/QT ratio. The clinical data and these ECG parameters were compared between groups.
There was no statistically significant difference between groups, regarding clinical data (all < 0.05). Among ECG parameters, heart rate, QRS width, QTc interval, and cQTd interval were similar between groups (all < 0.05). There were two important statistically significant findings of this research: The mean Tp-e interval was longer (ATR group: 72.4 ± 24.7, control group: 58.8 ± 14.5, : 0.01), and the Tp-e/QT ratio was higher (ATR group: 0.2 ± 0.1, control group: 0.16 ± 0.4, : 0.027) in the ATR group.
According to the ventricular repolarization disturbances found in this study, patients with ATR may be at a higher risk of ventricular arrhythmia than healthy people. As a result, ATR patients should be assessed for ventricular arrhythmia risk by an expert cardiologist.
本研究旨在通过将急性自发性跟腱断裂（ATR）手术患者与健康个体对照组进行比较，来检查其心室复极（VR）紊乱情况。
在2014年6月至2020年7月期间，对总共29例患者（28例男性，1例女性；平均年龄：40±9.78岁；范围21 - 66岁）进行回顾性分析，这些患者在受伤后的前三周内就诊于急诊科，被诊断为急性自发性ATR，并接受了开放性Krackow缝合技术治疗。从心脏病门诊招募了52名健康个体（47例男性，5例女性；平均年龄：39±11.45岁；范围21 - 66岁）作为对照组。从病历中收集临床数据（人口统计学特征和实验室参数（血糖、肌酐、血红蛋白、白细胞计数和血脂谱））和心电图（ECG）。对ECG进行心率和VR参数评估，包括QRS波宽度、QTc间期、cQTd间期、Tp - e间期和Tp - e/QT比值。对两组之间的临床数据和这些ECG参数进行比较。
在临床数据方面，两组之间无统计学显著差异（均P<0.05）。在ECG参数中，两组之间的心率、QRS波宽度、QTc间期和cQTd间期相似（均P<0.05）。本研究有两个重要的统计学显著发现：ATR组的平均Tp - e间期更长（ATR组：72.4±24.7，对照组：58.8±14.5，P = 0.01），且Tp - e/QT比值更高（ATR组：0.2±0.1，对照组：0.16±0.4，P = 0.027）。
根据本研究中发现的心室复极紊乱情况，ATR患者可能比健康人有更高的室性心律失常风险。因此，应由专业心脏病专家对ATR患者进行室性心律失常风险评估。
