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一项关于急诊就诊早期妊娠和并发症的全国性分析:对后罗伊美国的影响。

A national analysis of ED presentations for early pregnancy and complications: Implications for post-Roe America.

机构信息

Department of Emergency Medicine, Aventura Hospital and Medical Center, United States of America.

Department of Emergency Medicine, Aventura Hospital and Medical Center, United States of America.

出版信息

Am J Emerg Med. 2023 Aug;70:90-95. doi: 10.1016/j.ajem.2023.05.011. Epub 2023 May 22.

DOI:10.1016/j.ajem.2023.05.011
PMID:37245403
Abstract

BACKGROUND

Most obstetric emergencies are initially managed in the emergency department (ED). The Supreme Court decision of Dobbs v. Jackson Women's Health Organization, overturning Roe v. Wade, in June 2022, eliminated constitutional protection of abortion rights, allowing states to swiftly enact laws that can greatly change reproductive medicine. In this post-Roe landscape, the ambiguity and uncertainty being imposed on clinicians regarding the legality of certain interventions may have catastrophic effects. To understand and plan for the changes that will come and attempt to mitigate adverse outcomes, the authors first assessed the current state of pregnancy-related complication care in the ED setting. This study utilized data obtained from the National Hospital Ambulatory Medical Care Survey (NHAMCS) to evaluate trends in pregnancy-related ED visits from 2016 to 2020 that could be impacted by restricted abortion access and trigger laws. The authors subsequently analyzed the legislative changes and translated the pertinent ones to dispel misunderstandings and provide a framework for appropriate medical practice.

METHODS

The retrospective study utilized data from the NHAMCS database from 2016 to 2020, encompassing an estimated total of 4,556,778 pregnancy-related ED visits. NHAMCS is a multi-stage probabilistic sample collected by the National Center for Health Statistics (NCHS) at the Centers for Disease Control and Prevention (CDC) using an annual survey of EDs in the United States. All data were summarized using descriptive statistics such as proportions and 95% confidence intervals Furthermore, the supreme court decision was analyzed in addition to multiple state laws and legal texts. The findings were summarized and discussed.

RESULTS

The majority (79.4%) of all studied visits were for patients between the ages of 18-34 years, capturing those in peak reproductive years. This age group also comprised of the bulk (76.4%) of visits for pathologic pregnancies, including ectopic and molar pregnancies, and 79.8% of visits for a spontaneous miscarriage or threatened miscarriage in early pregnancy. Black patients accounted for 25.7%, white patients 70.1%. Regarding ethnicity, patients were separated into Hispanic and non-Hispanic, with Hispanic patients comprising 27% of all ED visits for included diagnoses between 2016 and 2020. Most visits for complications following an induced abortion occurred in the south (70.8%) and were nearly twice as likely to occur in non-metropolitan areas. Approximately 18% patients presenting with a pathologic pregnancy required admission to the hospital and approximately 50% of those visits for pathologic pregnancies and visits for bleeding in pregnancy had a procedure in the ED (49.8% and 49.5%). There were 111,264 estimated visits in which methotrexate was administered, amounting to approximately 1 in 7 visits for ectopic or molar pregnancy. In this data set, approximately 14,000 miscarriage and early bleeding patients received misoprostol.

CONCLUSION

Pregnancy-related ED visits comprise of a significant proportion of emergency care. As it relates to many of the trends previously elucidated on, the true extent of the burden cannot be predicted. It must be emphasized that contrary to popular belief, Dobbs v. Jackson does not prohibit termination of pregnancy in the setting of life-threatening conditions to the mother, including ectopic pregnancy, preeclampsia, and others, but the resultant uncertainty and ambiguity surrounding the constitutional change is leading to an over-compliance of the law, necessarily obstructing reproductive health care. The authors recommend that physicians be mindful of the rapidly-evolving laws in their particular state, and to also practice in accordance with Emergency Medical Treatment and Active Labor Act (EMTALA). Patient safety must be prioritized.

摘要

背景

大多数产科急症最初在急诊科(ED)进行管理。2022 年 6 月,最高法院推翻罗诉韦德案的多布斯诉杰克逊妇女健康组织案的裁决,取消了堕胎权利的宪法保护,允许各州迅速颁布可能极大改变生殖医学的法律。在这个后罗案的背景下,临床医生对某些干预措施的合法性所面临的模糊性和不确定性可能会产生灾难性的影响。为了了解和规划即将到来的变化,并试图减轻不利后果,作者首先评估了当前 ED 环境中与妊娠相关并发症护理的现状。本研究利用从 2016 年至 2020 年从全国医院门诊医疗保健调查(NHAMCS)中获得的数据,评估了因堕胎机会受限和触发法律而可能受到影响的与妊娠相关的 ED 就诊趋势。作者随后分析了立法变化,并将相关的变化翻译出来,以消除误解,并为适当的医疗实践提供框架。

方法

这项回顾性研究利用了 2016 年至 2020 年 NHAMCS 数据库的数据,估计总共涵盖了 4556778 例与妊娠相关的 ED 就诊。NHAMCS 是由美国疾病控制与预防中心(CDC)的国家卫生统计中心(NCHS)使用美国急诊的年度调查收集的多阶段概率样本。所有数据均使用比例和 95%置信区间等描述性统计进行总结。此外,还分析了最高法院的裁决以及多项州法律和法律文本。总结并讨论了研究结果。

结果

在所有研究就诊中,大多数(79.4%)是年龄在 18-34 岁之间的患者,他们处于生育高峰期。这个年龄组也构成了病理性妊娠就诊的大部分(76.4%),包括异位妊娠和葡萄胎妊娠,以及 79.8%的早期妊娠自然流产或先兆流产就诊。黑人患者占 25.7%,白人患者占 70.1%。在种族方面,患者分为西班牙裔和非西班牙裔,2016 年至 2020 年期间,西班牙裔患者占包括诊断在内的所有 ED 就诊的 27%。因人工流产后并发症就诊的大部分发生在南部(70.8%),并且在非都市区发生的可能性几乎是前者的两倍。大约 18%的病理性妊娠就诊患者需要住院治疗,大约 50%的病理性妊娠就诊和妊娠出血就诊患者在 ED 进行了手术(49.8%和 49.5%)。估计有 111264 次就诊使用了甲氨蝶呤,约占异位妊娠或葡萄胎就诊的 1/7。在这个数据集,约有 14000 例流产和早期出血患者接受了米索前列醇治疗。

结论

与妊娠相关的 ED 就诊构成了急诊护理的重要组成部分。就之前阐明的许多趋势而言,其实际负担无法预测。必须强调的是,与普遍看法相反,多布斯诉杰克逊案并没有禁止在危及母亲生命的情况下终止妊娠,包括异位妊娠、子痫前期等,但围绕宪法变更的不确定性和模糊性正在导致对法律的过度遵守,必然会阻碍生殖保健。作者建议医生注意其所在州不断变化的法律,并根据《紧急医疗治疗和积极劳动法案》(EMTALA)进行实践。必须优先考虑患者安全。

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