Wong O, Utidjian H M, Karten V S
J Occup Med. 1979 Feb;21(2):98-102. doi: 10.1097/00043764-197902000-00009.
An attempt has been made to examine retrospectively any antifertility influence of ethylene dibromide (EDB) by studying the reproductive performance of men exposed to EDB, exclusively on the basis of their reproductive histories in terms of live births to their wives, subsequent to their occupational exposure to EDB. The number of live, putatively legitimate, natural children born to the wives was compared to the expected number derived from national fertility tables published for successive birth cohorts of U.S. women by the National Center for Health Statistics. The indirect standardization method was used to adjust for the confounding effects of maternal age, parity, race and calendar year in deriving the expected births. The number of observed births was expressed as a percentage of the expected in assessing the workers' reproductive performance. One of the four plants studied showed a significant decrease in fertility.
有人试图通过研究接触二溴乙烷（EDB）的男性的生殖表现，专门依据他们职业接触EDB后其妻子的活产生育史，来回顾性地研究二溴乙烷的任何抗生育影响。将妻子生育的存活、假定合法的亲生子女数量与美国国家卫生统计中心为美国女性连续出生队列发布的全国生育表得出的预期数量进行比较。在推导预期出生数时，采用间接标准化方法来调整母亲年龄、胎次、种族和历年的混杂效应。在评估工人的生殖表现时，观察到的出生数表示为预期数的百分比。所研究的四家工厂中有一家显示生育率显著下降。
