Schmidt Casper, Laugesen Henning
Department of Communication and Psychology, Aalborg University, Rendsburggade 14, 9000 Aalborg, Denmark.
Addiction Psychiatric Clinic, Fuglebakkevej 54, 8210 Aarhus V, Denmark.
Epilepsy Behav Rep. 2023 May 9;22:100606. doi: 10.1016/j.ebr.2023.100606. eCollection 2023.
This case study examines how an intervention of infra-low frequency neurofeedback training (ILF-NFT) affects the symptomatology of an eight-year-old patient with Dravet syndrome (DS), a rare and highly disabling form of epilepsy. Our results demonstrate that ILF-NFT has improved the patient's sleep disturbance, has significantly reduced seizure frequency and severity, and has reversed neurodevelopmental decline, with positive development in intellectual and motor skills. No significant changes have been made to the patient's medication in the observed period of 2.5 years. Thus, we draw attention to ILF-NFT as a promising intervention in addressing DS symptomatology. Finally, we discuss the study's methodological limitations and warrant future studies to assess the effect of ILF-NFT in DS in more elaborate research designs.
本案例研究探讨了超低频神经反馈训练（ILF-NFT）干预如何影响一名八岁的德雷维特综合征（DS）患者的症状表现，DS是一种罕见且致残性很高的癫痫形式。我们的结果表明，ILF-NFT改善了患者的睡眠障碍，显著降低了癫痫发作的频率和严重程度，并扭转了神经发育衰退，在智力和运动技能方面有积极发展。在观察的2.5年期间，患者的药物治疗没有显著变化。因此，我们提请注意ILF-NFT作为一种有前景的干预措施来解决DS症状。最后，我们讨论了该研究的方法学局限性，并呼吁未来开展研究，以更精细的研究设计评估ILF-NFT对DS的影响。
