School of Physics and Electronic Information Engineering, Henan Polytechnic University, Jiaozuo, 454000, P. R. China.
College of Chemistry and Chemical Engineering, Henan Key Laboratory of Coal Green Conversion, Henan Polytechnic University, Jiaozuo 454000, P. R. China.
Anal Methods. 2023 Jun 8;15(22):2761-2765. doi: 10.1039/d3ay00516j.
The high toxicity of phosgene poses potential threats to public health and safety. In this work, a novel fluorescent probe was designed to detect phosgene using hydroxyl and pyrazole moieties as the recognition sites. The response to phosgene with probe 1 was fast (less than 30 s), highly selective and sensitive with the limit of detection being 4.78 nM in solution. Furthermore, probe 1 was employed to conveniently fabricate paper test strips for efficiently detecting phosgene gas. The limit of detection was obtained as 0.014 ppm by using a smartphone RGB app, revealing that probe 1 has good prospects for sensitively detecting phosgene gas.
光气毒性高，对公共健康和安全构成潜在威胁。在这项工作中，设计了一种新型荧光探针，以羟基和吡唑基为识别位点来检测光气。探针 1 对光气的响应速度快（不到 30 秒），选择性和灵敏度高，在溶液中的检测限为 4.78 nM。此外，探针 1 还被用于方便地制备纸测试条，以有效地检测光气气体。使用智能手机 RGB 应用程序，检测限达到 0.014 ppm，表明探针 1 具有灵敏检测光气气体的良好前景。
