Key Laboratory of Life-Organic Analysis of Shandong Province, Qufu Normal University, Qufu, 273165, China.
School of Chemical New Material Engineering, Shandong Polytechnic College, Jining, 272027, China.
Talanta. 2021 Jan 1;221:121477. doi: 10.1016/j.talanta.2020.121477. Epub 2020 Aug 1.
Due to the potential threats of phosgene and nitrite to public health and safety, in this work, we first proposed the application of a facile dual-function fluorescent probe 2-(1H-Benzimidazol-2-yl)Aniline (BMA) for the detection of phosgene and nitrite in different solvent environments. BMA had fast response (1 min), high selectivity and sensitivity (the limit of detection was 1.27 nM) to phosgene in CHCN solution (containing 10% DMSO), which manifested as a ratiometric fluorescent mode from 416 nm to 480 nm. The response of BMA to nitrite in HCl solution (pH = 1, containing 10% CHCN) was also highly selective and sensitive (the limit of detection was 60.63 nM), which shown as a turn-off fluorescent mode at 485 nm. In addition, two portable chemosensors (BMA-loaded TLC plates and test strips) had also been successfully manufactured for the detection of phosgene in the gas phase and nitrite in solution, which displayed good responses. Most importantly, BMA had also been successfully used for detection of nitrite in food samples, and a good recovery (88.5%-107.2%) was obtained by adding standard sodium nitrite.
由于光气和亚硝酸盐对公众健康和安全的潜在威胁，在这项工作中，我们首次提出了一种简便的双功能荧光探针 2-(1H-苯并咪唑-2-基)苯胺（BMA）在不同溶剂环境下用于检测光气和亚硝酸盐的应用。BMA 在 CHCN 溶液（含 10% DMSO）中对光气具有快速响应（1 分钟）、高选择性和灵敏度（检测限为 1.27 nM），表现为从 416nm 到 480nm 的比率荧光模式。BMA 在 HCl 溶液（pH = 1，含 10% CHCN）中对亚硝酸盐的响应也具有高度选择性和灵敏度（检测限为 60.63 nM），表现为在 485nm 处的荧光猝灭模式。此外，还成功制备了两种便携式化学传感器（负载 BMA 的 TLC 板和试条），用于检测气相中的光气和溶液中的亚硝酸盐，显示出良好的响应。最重要的是，BMA 还成功地用于检测食品样品中的亚硝酸盐，并通过添加标准亚硝酸钠获得了良好的回收率（88.5%-107.2%）。
