Likova Lora T, Zhou Zhangziyi, Liang Michael, Tyler Christopher W
Smith-Kettlewell Eye Research Institute, San Francisco.
IS&T Int Symp Electron Imaging. 2023 Jan;35. doi: 10.2352/EI.2023.35.10.HVEI-256.
How is the cortical navigation network reorganized by the Likova Cognitive-Kinesthetic Navigation Training? We measured Granger-causal connectivity of the frontal-hippocampal-insular-retrosplenial-V1 network of cortical areas before and after this one-week training in the blind. Primarily top-down influences were seen during two tasks of drawing-from-memory (drawing complex maps and drawing the shortest path between designated map locations), with the dominant role being congruent influences from the egocentric insular to the allocentric spatial retrosplenial cortex and the amodal-spatial sketchpad of V1, with concomitant influences of the frontal cortex on these areas. After training, and during planning-from-memory of the best on-demand path, the hippocampus played a much stronger role, with the V1 sketchpad feeding information forward to the retrosplenial region. The inverse causal influences among these regions generally followed a recursive feedback model of the opposite pattern to a subset of congruent influences. Thus, this navigational network reorganized its pattern of causal influences with task demands and the navigation training, which produced marked enhancement of the navigational skills.
利科娃认知 - 动觉导航训练如何重组皮层导航网络？我们在盲人进行为期一周的训练前后，测量了额叶 - 海马 - 脑岛 - retrosplenial - V1皮层区域网络的格兰杰因果连通性。在两项记忆绘图任务（绘制复杂地图和绘制指定地图位置之间的最短路径）中，主要观察到自上而下的影响，其中占主导地位的是从自我中心脑岛到异我中心空间retrosplenial皮层以及V1的非模态空间画板的一致性影响，同时额叶皮层对这些区域也有影响。训练后，在记忆规划最佳按需路径期间，海马体发挥了更强的作用，V1画板向前向retrosplenial区域传递信息。这些区域之间的反向因果影响通常遵循与一致性影响子集相反模式的递归反馈模型。因此，这个导航网络随着任务需求和导航训练重组了其因果影响模式，这显著提高了导航技能。
