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Time-resolved X-ray diffraction studies of the B in equilibrium D structural transition in the DNA double helix.

作者信息

Mahendrasingam A, Forsyth V T, Hussain R, Greenall R J, Pigram W J, Fuller W

出版信息

Science. 1986 Jul 11;233(4760):195-7. doi: 10.1126/science.3726529.

DOI:10.1126/science.3726529
PMID:3726529
Abstract

Because of the relation between topology and function, there has been much interest in the structural transitions of the various conformations of DNA polymers. The x-ray fiber diffraction analysis system at the Daresbury Synchrotron Radiation Source was used to study the reversible transition between the B and D forms of the synthetic DNA poly[d(A-T)].poly[d(A-T)]. The gradual progression of conformations between these two forms indicates that the DNA double helix does not undergo a change of handedness during this transition.

摘要

相似文献

1
Time-resolved X-ray diffraction studies of the B in equilibrium D structural transition in the DNA double helix.
Science. 1986 Jul 11;233(4760):195-7. doi: 10.1126/science.3726529.
2
Conformational transitions in oriented fibres of the synthetic polynucleotide poly[d(AT)].poly[d(AT)] double helix.合成多核苷酸聚[d(AT)].聚[d(AT)]双螺旋定向纤维中的构象转变。
Nature. 1983 Feb 10;301(5900):535-7. doi: 10.1038/301535a0.
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DNA hydration studied by neutron fiber diffraction.通过中子纤维衍射研究DNA水合作用。
Basic Life Sci. 1996;64:345-58. doi: 10.1007/978-1-4615-5847-7_30.
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X-ray fibre diffraction study of an elevated temperature structure of poly(dA).poly(dT).聚（dA）·聚（dT）高温结构的X射线纤维衍射研究
J Mol Biol. 1997 Nov 21;274(1):64-71. doi: 10.1006/jmbi.1997.1378.
6
Temperature effects on the structure of poly(dA).poly(dT): an X-ray fiber diffraction study.温度对聚（dA）·聚（dT）结构的影响：一项X射线纤维衍射研究。
C R Acad Sci III. 1997 Sep;320(9):735-9. doi: 10.1016/s0764-4469(97)84822-6.
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X-ray high-angle fibre diffraction studies of nucleic acid structure using the Daresbury Synchrotron Radiation Source.利用达累斯伯里同步辐射源对核酸结构进行X射线高角度纤维衍射研究。
Biochem Soc Trans. 1986 Jun;14(3):553-7. doi: 10.1042/bst0140553.
8
Poly(dA-dT).poly(dA-dT) in low salt appears to be a left-handed B-helix combined use of chemical theory, fiber diffraction and NMR spectroscopy.低盐状态下的聚（dA-dT）·聚（dA-dT）似乎是一种左旋B型螺旋，它综合运用了化学理论、纤维衍射和核磁共振光谱学。
J Biomol Struct Dyn. 1983 Oct;1(2):395-416. doi: 10.1080/07391102.1983.10507450.
9
The structure of poly(dA):poly(dT) in a condensed state and in solution.聚（dA）:聚（dT）在凝聚态和溶液中的结构。
Nucleic Acids Res. 1987 Jul 24;15(14):5833-44. doi: 10.1093/nar/15.14.5833.
10
Poly(dA).poly(dT) is a B-type double helix with a distinctively narrow minor groove.聚（dA）·聚（dT）是一种具有明显狭窄小沟的B型双螺旋结构。
Nature. 1987;325(6107):821-3. doi: 10.1038/325821a0.

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