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经尿道钬激光前列腺剜除术中同期行膀胱颈切开术的短期临床疗效

Short-Term Clinical Outcomes of Bladder Neck Incision at Time of Holmium Laser Enucleation of the Prostate.

机构信息

Department of Urology, Northwestern University, Chicago, Illinois, USA.

Department of Urology, Ohio State University, Columbus, Ohio, USA.

出版信息

J Endourol. 2023 Sep;37(9):1037-1042. doi: 10.1089/end.2022.0816. Epub 2023 Jun 30.

Abstract

The effect of prophylactic bladder neck incision (BNI) at time of holmium laser enucleation of the prostate (HoLEP) is unknown. The aim of our study was to examine HoLEP outcomes with a specific focus on rates of bladder neck contractures (BNCs), with and without utilizing prophylactic BNI. We performed a retrospective review of HoLEP patients from January 2021 until January 2022. Outcomes of patients who underwent BNI at time of HoLEP were compared with those who underwent standard HoLEP alone. Student's -tests, chi-square tests, and logistic regressions were performed using SAS Studio. In total, 421 patients underwent HoLEP. BNI was concurrently performed in 74 (17.6%) HoLEP patients. BNI patients were younger (67.5 ± 9.0 years 71.1 ± 8.2 years,  = 0.00007) and had smaller prostates (60.7 ± 30.3 cc 133.2 ± 64.5 cc,  < 0.0001). Procedure, enucleation, and morcellation times were shorter in the BNI group (all  < 0.0001). There was no statistical difference in same-day discharge rates (90.4% 87.7%,  = 0.5), short-term functional outcomes, emergency department (ED) visits, or readmission rates between the two groups. At 14 months mean follow-up, two BNCs occurred in patients in the control group (0.6%), and no BNCs occurred in patients who underwent BNI (0.0%,  = 0.5). BNI at time of HoLEP did not decrease the ability to achieve same-day discharge or increase 90-day complications, ED visits, or readmission rates. No BNCs occurred in patients who underwent prophylactic BNI (0.0%) despite a smaller gland size and lower specimen weight in this cohort. Further prospective studies are required to conclude if concurrent BNI at time of HoLEP is protective against BNC.

摘要

预防性膀胱颈部切开术(BNI)在钬激光前列腺剜除术(HoLEP)中的作用尚不清楚。本研究的目的是检查 HoLEP 的结果,特别关注是否存在膀胱颈部挛缩(BNC)的发生率,以及是否利用预防性 BNI。我们对 2021 年 1 月至 2022 年 1 月期间接受 HoLEP 的患者进行了回顾性分析。比较了同时行 BNI 与单纯行标准 HoLEP 的患者的结果。采用 SAS Studio 进行学生 t 检验、卡方检验和逻辑回归分析。共有 421 例患者接受了 HoLEP。同期行 BNI 者 74 例(17.6%)。BNI 组患者年龄更小(67.5±9.0 岁 71.1±8.2 岁,=0.00007),前列腺体积更小(60.7±30.3 cc 133.2±64.5 cc, < 0.0001)。BNI 组的手术、剜除和粉碎时间更短(均 < 0.0001)。两组的当日出院率(90.4% 87.7%,=0.5)、短期功能结局、急诊科(ED)就诊率和再入院率无统计学差异。在 14 个月的平均随访中,对照组有 2 例发生 BNC(0.6%),而行 BNI 组无 BNC(0.0%,=0.5)。HoLEP 时行 BNI 并不能降低实现当日出院的能力,也不会增加 90 天的并发症、ED 就诊率或再入院率。在这组患者中,尽管腺体较小且标本重量较轻,但行预防性 BNI 的患者均未发生 BNC(0.0%)。需要进一步的前瞻性研究来确定 HoLEP 时同期行 BNI 是否可以预防 BNC。

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